Evidence map›Paper›PMID 29301940›Full record

ArticleThe Journal of biological chemistry2018

The NLR family pyrin domain-containing 11 protein contributes to the regulation of inflammatory signaling.

Kornelia Ellwanger, Emily Becker, Ioannis Kienes, Anna Sowa, Yvonne Postma, Yamel Cardona Gloria, Alexander N R Weber, Thomas A Kufer

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. An overview of human inflammasomes: Activation and regulation.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Review
  3. Review
  4. Article
  5. Pattern Recognition by NOD-Like Receptors.Advances in experimental medicine and biology · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. The NLR gene family: from discovery to present day.Nature reviews. Immunology · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Inflammasomes-New Contributors to Blood Diseases.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kornelia EllwangerInstitute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany.
Emily BeckerInstitute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany.
Ioannis KienesInstitute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany.
Anna SowaInstitute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany.
Yvonne PostmaInstitute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany.
Yamel Cardona GloriaDepartment of Immunology, University of Tübingen, 72076 Tübingen, Germany.
Alexander N R WeberDepartment of Immunology, University of Tübingen, 72076 Tübingen, Germany.
Thomas A KuferInstitute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany. Electronic address: thomas.kufer@uni-hohenheim.de.
University of Hohenheim · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian Nod-like receptor (NLR) proteins contribute to the regulation and induction of innate and adaptive immunity in mammals, although the function of about half of the currently identified NLR proteins remains poorly characterized. Here we analyzed the function of the primate-specific

Indexed as

Down-RegulationGene Expression RegulationImmunity, InnateAmino Acid SubstitutionB-LymphocytesCell Line, TransformedCell Line, TumorFemaleGenes, ReporterHumansInterferon Type IIntracellular Signaling Peptides and ProteinsLipopolysaccharidesMaleMutationMyeloid CellsInterferon Type IIntracellular Signaling Peptides and ProteinsLipopolysaccharidesNeoplasm ProteinsNF-kappa BNLRP11 protein, humanNLR ProteinsPeptide FragmentsRecombinant Fusion Proteinsanti-viralB cellimmunologyinflammasomeinflammationinnate immunityinterferonlymphomaNF-kappa B (NF-KB)NLRP11Nod-like receptor (NLR)signaling

Identifiers

PMID29301940
PMCPMC5827450
OpenAlexW2781604850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.