Evidence map›Paper›PMID 29301795›Full record

ArticleBMJ case reports2018

Recurrent cytomegalovirus colitis: a rare case of immune reconstitution inflammatory syndrome.

Joseph Alukal, Mohammed Asif, Rachana Mundada, William B McNamee

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph AlukalDepartment of Internal Medicine, Mercy Fitzgerald Hospital, Darby, Pennsylvania, USA.
Mohammed AsifDepartment of Surgery, Mercy Fitzgerald Hospital, Darby, Pennsylvania, USA.
Rachana MundadaDepartment of Internal Medicine, Mercy Fitzgerald Hospital, Darby, Pennsylvania, USA.
William B McNameeDepartment of Internal Medicine-Infectious Disease, Mercy Fitzgerald Hospital, Darby, Pennsylvania, USA.
Mercy Fitzgerald Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) colitis usually occurs in patients with advanced immunosuppression when the CD4 count is <50 cells/μL. We reported a case of recurrent CMV colitis in a patient with HIV who presented with profuse lower gastrointestinal bleed. This was a case of immune reconstitution inflammatory syndrome (IRIS) manifesting as CMV colitis and has been reported only once in the literature previously. This patient had a CD4 count of 157 cells/μL and undetectable viral load after being on antiretroviral therapy (ART) for 5 months, which was consistent with IRIS. The diagnosis of CMV was confirmed by a colonoscopy and a biopsy. This case highlights the fact that CMV colitis can manifest despite a moderately preserved CD4 count and the clinicians must have a high index suspicion for IRIS syndrome especially when someone was recently started on ART. Since effective treatment is available, it is important not to miss the diagnosis of CMV colitis.

Indexed as

ColitisCytomegalovirusCytomegalovirus InfectionsFemaleGastrointestinal HemorrhageHIV InfectionsHumansImmune Reconstitution Inflammatory SyndromeMiddle AgedRecurrenceendoscopygastroenterologyHiv / Aidsinfection (gastroenterology)ulcer

Identifiers

PMID29301795
PMCPMC5787009
OpenAlexW2781951207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.