Evidence map›Paper›PMID 29301791›Full record

ArticleCancer research2018

Deletion of the von Hippel-Lindau Gene in Hemangioblasts Causes Hemangioblastoma-like Lesions in Murine Retina.

Herui Wang, Matthew J Shepard, Chao Zhang, Lijin Dong, Dyvon Walker, Liliana Guedez, Stanley Park, Yujuan Wang, Shida Chen, Ying Pang and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Herui WangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Matthew J ShepardSurgical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland.
Chao ZhangSurgical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland.
Lijin DongNational Eye Institute, NIH, Bethesda, Maryland.
Dyvon WalkerSurgical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland.
Liliana GuedezNational Eye Institute, NIH, Bethesda, Maryland.
Stanley ParkNational Eye Institute, NIH, Bethesda, Maryland.
Yujuan WangNational Eye Institute, NIH, Bethesda, Maryland.
Shida ChenNational Eye Institute, NIH, Bethesda, Maryland.
Ying PangEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland.
Qi ZhangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
Chun GaoNational Eye Institute, NIH, Bethesda, Maryland.
Wai T WongNational Eye Institute, NIH, Bethesda, Maryland.
Henry WileyNational Eye Institute, NIH, Bethesda, Maryland.
Karel PacakEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland.
Emily Y ChewNational Eye Institute, NIH, Bethesda, Maryland.
Zhengping ZhuangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland. chanc@nei.nih.gov zhengping.zhuang@nih.gov.
Chi-Chao ChanNational Eye Institute, NIH, Bethesda, Maryland. chanc@nei.nih.gov zhengping.zhuang@nih.gov.
Sun Yat-sen University · CN

Funding

Diagnosis, Pathophysiology And Molecular Biology of Pheochromocytoma and ParagangliomaZIAHD008735 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PACAK, KAREL · 2009 to 2024
$28.4M
NEI Genetic Engineering CoreZICEY000458 · NEI · NATIONAL EYE INSTITUTE · PI DONG, LIJIN · 2009 to 2025
$22.6M
Hypoxia signaling in cancer developmentZIABC011773 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ZHUANG, ZHENGPING · 2017 to 2025
$13.0M
Histopathology CoreZICEY000461 · NEI · NATIONAL EYE INSTITUTE · PI SCHNEEWEIS, DAVID · 2009 to 2022
$7.7M
Molecular And Immunopathology Of Experimental And Clinical Ocular DiseasesZIAEY000222 · NEI · NATIONAL EYE INSTITUTE · PI CHAN, CHI-CHAO · 2009 to 2015
$7.2M
NEI Intramural Biorepository for Retinal Diseases (12-EI-0042)ZIAEY000514 · NEI · NATIONAL EYE INSTITUTE · PI KEENAN, TIARNAN · 2012 to 2025
$2.0M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA EY000222Intramural NIH HHS ZIA EY000514Intramural NIH HHS ZIA HD008735Intramural NIH HHS ZIC EY000461NEI NIH HHS ZIA EY000222NEI NIH HHS ZIA EY000514NEI NIH HHS ZIC EY000461
6 · The paper itself

Abstract

von Hippel-Lindau (VHL) disease is an autosomal-dominant tumor predisposition syndrome characterized by the development of highly vascularized tumors and cysts. LOH of the

Indexed as

Disease Models, AnimalSequence DeletionAnimalsBiomarkers, TumorFemaleHemangioblastomaHemangioblastsMaleMiceMice, KnockoutRetinal Neoplasmsvon Hippel-Lindau DiseaseVon Hippel-Lindau Tumor Suppressor ProteinBiomarkers, TumorVHL protein, mouseVon Hippel-Lindau Tumor Suppressor Protein

Identifiers

PMID29301791
PMCPMC7446935
OpenAlexW2781651057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.