Evidence map›Paper›PMID 29301496›Full record

ArticleBMC neurology2018

MR imaging features of benign retroperitoneal paragangliomas and schwannomas.

Yanguang Shen, Yan Zhong, Haiyi Wang, Lu Ma, Yingwei Wang, Kun Zhang, Zhonghua Sun, Huiyi Ye

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Mutation spectrum and clinical features of MYORG in Iranian patients with Primary Familial Brain Calcification (PFBC).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Computed tomography angiography features of a retroperitoneal extra-adrenal paraganglioma in a cat.The Canadian veterinary journal = La revue veterinaire canadienne · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Solid Primary Retroperitoneal Masses in Adults: An Imaging Approach.The Indian journal of radiology & imaging · 2022
    Article
  14. Review
  15. Review
  16. Adrenal Schwannoma: A Case Report.International medical case reports journal · 2021
    Article
  17. Update on MR Imaging of cystic retroperitoneal masses.Abdominal radiology (New York) · 2020
    Review
  18. Adrenal schwannoma: a case report.BJR case reports · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yanguang ShenDepartment of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box, Beijing, 100853, China.
Yan ZhongDepartment of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box, Beijing, 100853, China.
Haiyi WangDepartment of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box, Beijing, 100853, China.
Lu MaDepartment of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box, Beijing, 100853, China.
Yingwei WangDepartment of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box, Beijing, 100853, China.
Kun ZhangDepartment of Radiology, Chinese Navy General Hospital, Beijing, China.
Zhonghua SunDepartment of Medical Radiation Sciences, Curtin University, Perth, 6102, Australia.
Huiyi YeDepartment of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box, Beijing, 100853, China. 13701100368@163.com.
Chinese PLA General Hospital · CNCurtin University · AUPLA Navy General Hospital · CN

Funding

Health Care Special Project 14BJZ02National Natural Science Foundation of China 81271535
6 · The paper itself

Abstract

backgroundTo determine whether MRI feature analysis can differentiate benign retroperitoneal extra-adrenal paragangliomas and schwannomas.

methodsThe MRI features of 50 patients with confirmed benign retroperitoneal extra-adrenal paragangliomas and schwannomas were retrospectively reviewed by two radiologists blinded to the histopathologic diagnosis. These features were compared between two types of tumours by use of the Mann-Whitney test and binary logistic regression. The patients' clinical characteristics were reviewed.

resultsAnalysis of MRI images from 50 patients revealed no significant differences in the quantitative MRI features of lesion size, ratio of diameter and apparent diffusion coefficient. There were significant differences in the qualitative MRI features of location, necrosis, cysts and degree of tumour enhancement for two readers, with no significant differences in the other qualitative MRI features between these tumours. The combination of necrosis with degree of tumour enhancement during the arterial phase increased the probability that a retroperitoneal mass would represent retroperitoneal extra-adrenal paraganglioma as opposed to schwannoma.

conclusionWe have presented the largest series of MRI features of both benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Some MRI features assist in the differentiation between these tumours, with imaging features consisting of necrosis and avid enhancement during the arterial phase, suggestive of retroperitoneal extra-adrenal paragangliomas.

Indexed as

HumansMagnetic Resonance ImagingNeurilemmomaParagangliomaRetroperitoneal NeoplasmsRetrospective StudiesMagnetic resonance imagingParagangliomaRetroperitoneal spaceSchwannoma

Identifiers

PMID29301496
PMCPMC5753505
OpenAlexW2782252630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.