ArticleBMC genomics2018
Molecular characterization of larval development from fertilization to metamorphosis in a reef-building coral.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 64 citations in OpenAlex.
- Efficient genome editing using CRISPR-Cas9 in reef-building corals.Nature protocols · 2026Review
- Major transitions in early coral development: novel insights enabled by visualisation of a comprehensive transcriptomic dataset for Acropora millepora.BMC biology · 2026Article
- Coral larval proteomics at onset of metamorphosis highlights innate immunity maturation in parallel to neuro-sensing and skeletal development.Frontiers in physiology · 2026Article
- Spatially resolved gene expression analysis illuminates location-specific functions in the reef-building coral Pocillopora acuta.PloS one · 2026Article
- Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance.Communications biology · 2025Article
- Bacterial regulation of coral larval metamorphosis and settlement in Pocillopora damicornis.Communications biology · 2025Article
- Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata.EvoDevo · 2025Article
- A transcriptome-wide analysis provides novel insights into how Metabacillus indicus promotes coral larvae metamorphosis and settlement.BMC genomics · 2024Article
- Multiomics data integration, limitations, and prospects to reveal the metabolic activity of the coral holobiont.FEMS microbiology ecology · 2024Review
- Opsin expression varies across larval development and taxa in pteriomorphian bivalves.Frontiers in neuroscience · 2024Article
- Parallels and contrasts between the cnidarian and bilaterian maternal-to-zygotic transition are revealed in Hydractinia embryos.PLoS genetics · 2023Article
- Parallels and contrasts between the cnidarian and bilaterian maternal-to-zygotic transition are revealed inbioRxiv : the preprint server for biology · 2023Article
- Photodegradation of a bacterial pigment and resulting hydrogen peroxide release enable coral settlement.Scientific reports · 2023Article
- Predictive models for the selection of thermally tolerant corals based on offspring survival.Nature communications · 2022Article
- Gene expression alterations from reversible to irreversible stages during coral metamorphosis.Zoological letters · 2022Article
- Developmental series of gene expression clarifies maternal mRNA provisioning and maternal-to-zygotic transition in a reef-building coral.BMC genomics · 2021Article
- Combined responses of primary coral polyps and their algal endosymbionts to decreasing seawater pH.Proceedings. Biological sciences · 2021Article
- Life-history traits ofEcology and evolution · 2020Article
- Differential gene expression during substrate probing in larvae of the Caribbean coral Porites astreoides.Molecular ecology · 2019Article
- Neuroactive compounds induce larval settlement in the scleractinian coral Leptastrea purpurea.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMolecular mechanisms underlying coral larval competence, the ability of larvae to respond to settlement cues, determine their dispersal potential and are potential targets of natural selection. Here, we profiled competence, fluorescence and genome-wide gene expression in embryos and larvae of the reef-building coral Acropora millepora daily throughout 12 days post-fertilization.
resultsGene expression associated with competence was positively correlated with transcriptomic response to the natural settlement cue, confirming that mature coral larvae are "primed" for settlement. Rise of competence through development was accompanied by up-regulation of sensory and signal transduction genes such as ion channels, genes involved in neuropeptide signaling, and G-protein coupled receptor (GPCRs). A drug screen targeting components of GPCR signaling pathways confirmed a role in larval settlement behavior and metamorphosis.
conclusionsThese results gives insight into the molecular complexity underlying these transitions and reveals receptors and pathways that, if altered by changing environments, could affect dispersal capabilities of reef-building corals. In addition, this dataset provides a toolkit for asking broad questions about sensory capacity in multicellular animals and the evolution of development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.