Evidence map›Paper›PMID 29301320›Full record

ArticleInternational journal of molecular sciences2018

The Effects of Kaempferol-Inhibited Autophagy on Osteoclast Formation.

Chang-Ju Kim, Sang-Hun Shin, Bok-Joo Kim, Chul-Hoon Kim, Jung-Han Kim, Hae-Mi Kang, Bong-Soo Park, In-Ryoung Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Network pharmacology andArchives of medical science : AMS · 2026
    Article
  3. Kaempferol-A Natural Drug for Rheumatoid Arthritis.Chinese journal of integrative medicine · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. TGF-β3 Restrains Osteoclastic Resorption Through Autophagy.Bioengineering (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chang-Ju KimDepartment of Oral and Maxillofacial Surgery, Pusan National University Dental Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si 50612, Gyeongsangnam-do, Korea. changju75@hanmail.net.
Sang-Hun ShinDepartment of Oral and Maxillofacial Surgery, Pusan National University Dental Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si 50612, Gyeongsangnam-do, Korea. ssh8080@pusan.ac.kr.
Bok-Joo KimDepartment of Oral and Maxillofacial Surgery, Medical center, Dong-A University, 26, Daesingongwon-ro, Seo-gu, Busan 49201, Korea. samehope@naver.com.
Chul-Hoon KimDepartment of Oral and Maxillofacial Surgery, Medical center, Dong-A University, 26, Daesingongwon-ro, Seo-gu, Busan 49201, Korea. bbp2000@hanmail.net.
Jung-Han KimDepartment of Oral and Maxillofacial Surgery, Medical center, Dong-A University, 26, Daesingongwon-ro, Seo-gu, Busan 49201, Korea. noenemyguy@hanmail.net.
Hae-Mi KangBK21 PLUS Project, School of Dentistry, Pusan National University, Busandaehak-ro, 49, Mulguem-eup, Yangsan-si 50612, Gyeongsangnam-do, Korea. khaemi90@naver.com.
Bong-Soo ParkBK21 PLUS Project, School of Dentistry, Pusan National University, Busandaehak-ro, 49, Mulguem-eup, Yangsan-si 50612, Gyeongsangnam-do, Korea. parkbs@pusan.ac.kr.
In-Ryoung KimDepartment of Oral Anatomy, School of Dentistry, Pusan National University, Busandaehak-ro, 49, Mulguem-eup, Yangsan-si 50612, Gyeongsangnam-do, Korea. biowool@pusan.ac.kr.ORCID 0000-0003-0232-0385
Pusan National University · KRPusan National University Dental Hospital · KRDong-A University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kaempferol, a flavonoid compound, is derived from the rhizome of

Indexed as

AnimalsApoptosisAutophagyBone ResorptionCell DifferentiationGene Expression RegulationKaempferolsMiceOsteoclastsOsteogenesisProteolysisRANK LigandRAW 264.7 CellsRNA, MessengerSequestosome-1 ProteinkaempferolKaempferolsRANK LigandRNA, MessengerSequestosome-1 ProteinSqstm1 protein, mouseautophagybisphosphonate-related osteonecrosis of the jaw (BRONJ)bone remodelingflavonoidsosteoclast differentiationosteoporosis

Identifiers

PMID29301320
PMCPMC5796074
OpenAlexW2781679508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.