Evidence map›Paper›PMID 29301301›Full record

ArticleMolecules (Basel, Switzerland)2018

Immunosuppressive Effect of Geniposide on Mitogen-Activated Protein Kinase Signalling Pathway and Their Cross-Talk in Fibroblast-Like Synoviocytes of Adjuvant Arthritis Rats.

Feng Li, Miaomiao Dai, Hong Wu, Ran Deng, Jun Fu, Zhengrong Zhang, Li Dai, Wenyu Wang, Xuejing Dai, Xiang Zhan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Feng LiCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. wuhongprof@aliyun.com.
Miaomiao DaiHefei Anderson Pharmaceutical Co., Ltd., Hefei 230088, Anhui, China. fengli92@aliyun.com.
Hong WuCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. wuhuancpu@ahtcm.edu.cn.
Ran DengCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. dengran94@aliyun.com.
Jun FuCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. fujun6866@163.com.
Zhengrong ZhangCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. zhangzhengrong311@126.com.
Li DaiCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. daili6daisy@163.com.
Wenyu WangCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. 18605538039@163.com.
Xuejing DaiCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. daixuejing@aliyun.com.
Xiang ZhanCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. 18756935995@163.com.
Yan WangCollege of Pharmacy, Anhui University of Chinese Medicine, Key Laboratory of Modernized Chinese, Medicine in Anhui Province, Hefei 230012, Anhui, China. awangyan@163.com.
Anhui University of Traditional Chinese Medicine · CNHefei University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Geniposide (GE), an iridoid glycoside compound derived from

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalArthritis, ExperimentalCell ProliferationCell SurvivalImmunosuppressive AgentsInterferon-gammaInterleukin-17Interleukin-4IridoidsJointsMAP Kinase Signaling Systemp38 Mitogen-Activated Protein KinasesPhosphorylationRats, Sprague-DawleySynoviocytesAnti-Inflammatory Agents, Non-SteroidalgeniposideIl17a protein, ratImmunosuppressive AgentsInterferon-gammaInterleukin-17Interleukin-4Iridoidsp38 Mitogen-Activated Protein KinasesTransforming Growth Factor beta1adjuvant arthritiscross-talkfibroblast-like synoviocytesgeniposideMAPK signallingrheumatoid arthritis

Identifiers

PMID29301301
PMCPMC6017018
OpenAlexW2781997994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.