Evidence map›Paper›PMID 29301300›Full record

ArticleMolecules (Basel, Switzerland)2018

The Impact of Lipid Types and Liposomal Formulations on Osteoblast Adiposity and Mineralization.

Shun-Fu Chang, Chih-Chang Yeh, Pin-Jyun Chen, Hsin-I Chang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shun-Fu ChangDepartment of Medical Research and Development, Chang Gung Memorial Hospital Chiayi Branch, Chiayi 61363, Taiwan. sfchang@cgmh.org.tw.
Chih-Chang YehDepartment of Orthopaedics, Chiayi Branch, Taichung Veterans General Hospital, No. 600, Sec. 2, Shixian Road, West District, Chiayi City 60090, Taiwan. yeh215kimo@yahoo.com.tw.
Pin-Jyun ChenDepartment of Biochemical Science and Technology, National Chia Yi University, No. 300, Syuefu Rd, Chiayi City 60004, Taiwan. linda041134@gmail.com.
Hsin-I ChangDepartment of Biochemical Science and Technology, National Chia Yi University, No. 300, Syuefu Rd, Chiayi City 60004, Taiwan. hchang@mail.ncyu.edu.tw.
National Chiayi University · TWChiayi Chang Gung Memorial Hospital · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have demonstrated that fat accumulation in bone cells is detrimental to bone mass. Both adipocytes and osteoblasts are derived from common multipotent mesenchymal stem cells (MSCs) and hence the presence of fat may increase adipocyte proliferation, differentiation and fat accumulation while inhibiting osteoblast differentiation and bone formation. Lipids are common constituents in supramolecular vesicles (e.g., micelles or liposomes) that serve as drug delivery systems. Liposomal formulations such as Meriva

Indexed as

AnimalsCalcification, PhysiologicCationsCell DifferentiationCell LineCell SurvivalCholesterolCyclooxygenase 2Drug Delivery SystemsFatty Acids, MonounsaturatedLipid DropletsLipidsLiposomesMatrix Metalloproteinase 3MiceOsteoblasts1,2-dioleoyloxy-3-(trimethylammonium)propaneCationsCholesterolCyclooxygenase 2Fatty Acids, MonounsaturatedLipidsLiposomesMatrix Metalloproteinase 3Mmp3 protein, mousePhosphatidylcholinesPtgs2 protein, mouseQuaternary Ammonium Compoundslipidlipid droplet accumulationliposomal formulationosteoblastosteogenesis

Identifiers

PMID29301300
PMCPMC6017718
OpenAlexW2781937428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.