ArticleKorean Journal of Spine2017
Whole Spine Disc Degeneration Survey according to the Ages and Sex Using Pfirrmann Disc Degeneration Grades.
Article in Korean Journal of Spine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Adjacent segment degeneration after fusion spinal surgery-a systematic review.International orthopaedics · 2019Pooled it
- Preoperative mid-cervical disc degeneration is associated with residual cervical kyphosis after surgery for adolescent idiopathic scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Age-related changes in dorsal and ventral vertebral body height of the T12 vertebra in females: A magnetic resonance imaging study.Medicine · 2026Article
- Predictors of Interbody Fusion and Adjacent Segment Disease Following Anterior Lumbar Interbody Fusion for Degenerative Pathologies.Journal of clinical medicine · 2026Article
- Does congenital cervical fusion predispose to adjacent segment degeneration? A retrospective cohort study.BMC musculoskeletal disorders · 2026Article
- Immunohistochemical analysis to detect a molecular signature in intervertebral disc degeneration.Histochemistry and cell biology · 2025Article
- Concurrent changes in disability caused by back and neck pain after lumbar spine surgery: a multigroup trajectory analysis.Journal of orthopaedic surgery and research · 2025Article
- Enhanced disc regeneration through CRISPR/Cas9-mediated SOX9 and TGFβ1 coexpression in tonsil-derived mesenchymal stromal cells.Stem cell research & therapy · 2025Article
- Comparison of lumbar disc degeneration grading between deep learning model SpineNet and radiologist: a longitudinal study with a 14-year follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Progression of lumbar disc degeneration: A 14-year follow-up study examining Pfirrmann grading and its individual disc components.Acta radiologica open · 2025Article
- Sociodemographic Influences on Lumbar Disc Degeneration Severity and the Diagnostic Potential of Disc‑CSF Signal Ratio: Insights from a South East Asia Population Study.Journal of the Belgian Society of Radiology · 2025Article
- Male spondyloarthritis patients and those with longer disease duration have less severe disc degeneration: propensity score-matched comparison.Rheumatology advances in practice · 2024Article
- Degenerative cervical spine changes among early career fighter pilots: a 5-year follow-up.BMJ military health · 2023Article
- Epidemiology of Lumbar Degenerative Phenotypes of Children and Adolescents: A Large-Scale Imaging Study.Global spine journal · 2023Article
- MRI-based measurement of in vivo disc mechanics in a young population due to flexion, extension, and diurnal loading.JOR spine · 2023Article
- Cervical kinematic change after posterior full-endoscopic cervical foraminotomy for disc herniation or foraminal stenosis.PloS one · 2023Article
- Early Postoperative Loss of Disc Height Following Transforaminal and Lateral Lumbar Interbody Fusion: A Radiographic Analysis.Asian spine journal · 2022Article
- Is There Any Association between the Severity of Disc Degeneration and Low Back Pain?Revista brasileira de ortopedia · 2022Article
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Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePfirrmann disc grade is a useful scoring tool for evaluating disc degeneration, but normal values according to aging process has not been elucidated. This study was conducted to identify the prevalence and pattern of whole spine disc degeneration according to ages and gender differences.
methodsTotal 653 patients (336 male and 317 female patients, 48.1±58.7 years old) who took whole spine magnetic resonance images were enrolled in this study. There were 19 cases in their 2nd decades and 74 cases in 3rd decades, 141 cases in 4th decades, 129 cases in 5th decades, 139 cases in 6th decades, and 93 cases in 7th decades, 58 cases in over 8th decades. Pfirrmann disc grades were measured according to sex and ages by 2 neurosurgeons that were blind to this study.
resultsAll spinal disc degeneration grades were correlated with ageing. The Pfirrmann disc grades of degeneration in all spine levels showed the statistically significant difference according to the ages (p<0.001). The common Pfirrmann disc grades according to the ages were grade 3 among 2nd to 5th decades, and grade 4 was more common than 6th decades. The lower cervical level (C2-3 to C4-5) and lumbar level (L1-2 to L5-S1) were happened relatively early severe disc degeneration compared to other levels. The intersexual differences were increased after 6th decades.
conclusionDisc degeneration is natural course after one's 2nd decades. And its incidence and grade were increased with age, and more affected by sexual difference after 6th decades.
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