ReviewEndocrinology2018
Identifying the Critical Gaps in Research on Sex Differences in Metabolism Across the Life Span.
Review in Endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Elevated fasting glucose and triglycerides in combined oral contraceptive users compared to naturally cycling females.Physiological reports · 2026Article
- Are there sex differences in the variability of fasting metabolism?Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Microvascular Aging and Eicosanoids-Women's Evaluation of Systemic Aging Tenacity ("You are never too old to become younger!") Specialized Center of Research Excellence on Sex Differences Career Enhancement Core: Building the Future.Journal of women's health (2002) · 2023Article
- Article
- Serine, N-acetylaspartate differentiate adolescents with juvenile idiopathic arthritis compared with healthy controls: a metabolomics cross-sectional study.Pediatric rheumatology online journal · 2022Article
- Article
- Insight into genetic, biological, and environmental determinants of sexual-dimorphism in type 2 diabetes and glucose-related traits.Frontiers in cardiovascular medicine · 2022Review
- Sexual Dimorphism in Metabolic Responses to Western Diet inBiomolecules · 2021Article
- Intrinsic exercise capacity induces divergent vascular plasticity via arachidonic acid-mediated inflammatory pathways in female rats.Vascular pharmacology · 2021Article
- Postprandial hyperglycemia in type 2 diabetes and obstructive sleep apnea.Sleep medicine · 2021Article
- Is Being Physically Active Enough to Be Metabolically Healthy? The Key Role of Sedentary Behavior.Diabetes care · 2021Article
- Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis.Genome research · 2020Article
- Sex differences in infant blood metabolite profile in association with weight and adiposity measures.Pediatric research · 2020Article
- Approaching Sex Differences in Cardiovascular Non-Coding RNA Research.International journal of molecular sciences · 2020Review
- Sex Differences Across the Lifespan: A Focus on Cardiometabolism.Journal of women's health (2002) · 2020Article
- Sex Chromosomes Are Severely Disrupted in Gastric Cancer Cell Lines.International journal of molecular sciences · 2020Article
- Sexual Dimorphism of NAFLD in Adults. Focus on Clinical Aspects and Implications for Practice and Translational Research.Journal of clinical medicine · 2020Review
- Sex-related differences in self-care behaviors of adults with type 2 diabetes mellitus.Endocrine · 2020Article
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The National Institutes of Health (NIH) Office of Research in Women's Health now functions under a mandate calling for the systematic inclusion of both female and male cells, animals, and human subjects in all types of research, so that sex as a biological variable is understood in health and disease. Sex-specific data can improve disease prevention, diagnosis, and treatment as well as reduce inequities. Inclusion of women in research studies has modestly improved over the last 20 years, yet preclinical research is still primarily done using male animal models and male-derived cells, with the result that many conclusions are made based on incomplete and sex-biased data. There are important, yet poorly studied, sex differences in cardiometabolic disease. To begin to address these sex differences, the Center for Women's Health Research at the University of Colorado held its inaugural National Conference, "Sex Differences Across the Lifespan: A Focus on Metabolism," in September 2016 (cwhr@ucdenver.edu). Research to address the important goal of understanding key sex differences in cardiometabolic disease across the life span is lacking. The goal of this article is to discuss the current state of research addressing sex differences in cardiometabolic health across the life span, to outline critical research gaps that must be addressed in response to NIH mandates, and, importantly, to develop strategies to address sex as a biological variable to understand disease mechanisms as well as develop diagnostic and therapeutic modalities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.