ArticleThe journal of nutrition, health & aging2018
Serum Concentrations of 25-Hydroxyvitamin D and Depression in a General Middle-Aged to Elderly Population in Finland.
Article in The journal of nutrition, health & aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vitamin D and depression in adults: A systematic review.Biomolecules & biomedicine · 2025Pooled it
- Article
- The Role of Vitamin D in the Management of Major Depressive Disorder: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Can Vıtamın D Reduce the Need for SSRI by Modulatıng Serotonın Synthesıs?: A Revıew of Recent Lıterature.Current nutrition reports · 2025Review
- Is Vitamin D Important in Anxiety or Depression? What Is the Truth?Current nutrition reports · 2022Review
- Lower Blood Vitamin D Levels Are Associated with Depressive Symptoms in a Population of Older Adults in Kuwait: A Cross-Sectional Study.Nutrients · 2022Article
- Serum Vitamin D as a Biomarker in Autoimmune, Psychiatric and Neurodegenerative Diseases.Diagnostics (Basel, Switzerland) · 2022Review
- Vitamin D, Depressive Symptoms, and Covid-19 Pandemic.Frontiers in neuroscience · 2021Article
- Serum Vitamin D and Depressive Symptomatology among Boston-Area Puerto Ricans.The Journal of nutrition · 2020Article
- Lower serum 25-hydroxycholecalciferol is associated with depressive symptoms in older adults in Southern Brazil.Nutrition journal · 2020Article
- Effect of Viewing Video Representation of the Urban Environment and Forest Environment on Mood and Level of Procrastination.International journal of environmental research and public health · 2020Article
- Bone Metabolism in Patients Treated for Depression.International journal of environmental research and public health · 2020Article
- Review
- Editorial: Vitamin D: Does the Emperor Have No Clothes?The journal of nutrition, health & aging · 2019Article
- The prevalence of depressive symptoms in Chinese longevous persons and its correlation with vitamin D status.BMC geriatrics · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesLow concentrations of serum 25-hydroxyvitamin D [25(OH)D] have been postulated to associate with an increased prevalence of depression. As there are a limited number of publications on this issue, we examined the association between serum 25(OH)D and depression in a general middle-aged or older population.
designA population-based cross-sectional study. SETTING AND
participantsA total of 1602 men and women from the population-based Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) in Eastern Finland, aged 53-73 y in 1998-2001, were analysed. MEASUREMENTS: Depressive symptoms were assessed with the DSM-III depression scale, and those individuals who had scores over 4 (range 0-12) or had reported undergoing current antidepressant therapy, were considered as suffering from depression. Associations were estimated in serum 25(OH)D tertiles using logistic regression.
resultsAmong the participants, 183 subjects (11.4%) were considered to have depression. The mean age of the subjects was 62.6 years (SD 6.4, range 53.4-73.8 years). The mean serum 25(OH)D concentration was 43.8 nmol/L (SD 17.7, range 8.5-112.8 nmol/L), concentrations <50 nmol/L were observed in 65.0% of the subjects, and only 5.0% displayed concentrations ≥75 nmol/L. After multivariable adjustments, the odds ratios for having depression in the tertiles (from highest to the lowest) of serum 25(OH)D were 1, 1.35 (95 % CI: 0.87, 2.09) and 1.64 (95 % CI: 1.03, 2.59), P for trend=0.036.
conclusionThese findings indicate that a lower concentration of serum 25(OH)D is associated with a higher prevalence of depression in an elderly general population.
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