Evidence map›Paper›PMID 29300281›Full record

Observational studyThe journal of trauma and acute care surgery2018

The intraosseous have it: A prospective observational study of vascular access success rates in patients in extremis using video review.

Kristen M Chreiman, Ryan P Dumas, Mark J Seamon, Patrick K Kim, Patrick M Reilly, Lewis J Kaplan, Jason D Christie, Daniel N Holena

Abstract readObservational Study
In one paragraph

Observational study in The journal of trauma and acute care surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Enhanced Trauma Video Review With Computer Vision: Trauma Resuscitation Phase Segmentation and Procedure Detection.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Future perspectives of higher standards for trauma teams' organization, support, and evaluation.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Review
  12. Article
  13. Article
  14. Evaluation of validity and reliability of video analysis and live observations to assess trauma team performance.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Intraosseous access in the resuscitation of trauma patients: a literature review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristen M ChreimanFrom the Division of Traumatology, Surgical Critical Care and Emergency Surgery (K.M.C., R.P.D., M.J.S., P.K.K., P.M.R., L.J.K., D.N.H.), Division of Pulmonary and Critical Care (J.D.C.), and Center for Clinical Epidemiology and Biostatistics (J.D.C.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Ryan P Dumas
Mark J Seamon
Patrick K Kim
Patrick M Reilly
Lewis J Kaplan
Jason D Christie
Daniel N Holena

Funding

Reducing mortality attributable to cardiac and pulmonary complications after traumatic injury: understanding the role of failure-to-rescueK08HL131995 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HOLENA, DANIEL NORMAN · 2016 to 2018
$509k
NHLBI NIH HHS K08 HL131995
6 · The paper itself

Abstract

backgroundQuick and successful vascular access in injured patients arriving in extremis is crucial to enable early resuscitation and rapid OR transport for definitive repair. We hypothesized that intraosseous (IO) access would be faster and have higher success rates than peripheral intravenous (PIV) or central venous catheters (CVCs).

methodsHigh-definition video recordings of resuscitations for all patients undergoing emergency department thoracotomy from April 2016 to July 2017 were reviewed as part of a quality improvement initiative. Demographics, mechanism of injury, access type, access location, start and stop time, and success of each vascular access attempt were recorded. Times to completion for access types (PIV, IO, CVC) were compared using Kruskal-Wallis test adjusted for multiple comparisons, while categorical outcomes, such as success rates by access type, were compared using χ test or Fisher's exact test.

resultsStudy patients had a median age of 30 years (interquartile range [IQR], 25-38 years), 92% were male, 92% were African American, and 93% sustained penetrating trauma. A total of 145 access attempts in 38 patients occurred (median, 3.8; SD, 1.4 attempts per patient). There was no difference between duration of PIV and IO attempts (0.63; IQR, 0.35-0.96 vs. 0.39 IQR, 0.13-0.65 minutes, adjusted p = 0.03), but both PIV and IO were faster than CVC attempts (3.2; IQR, 1.72-5.23 minutes; adjusted p < 0.001 for both comparisons). Intraosseous lines had higher success rates than PIVs or CVCs (95% vs. 42% vs. 46%, p < 0.001).

conclusionAccess attempts using IO are as fast as PIV attempts but are more than twice as likely to be successful. Attempts at CVC access in patients in extremis have high rates of failure and take a median of over 3 minutes. While IO access may not completely supplant PIVs and CVCs, IO access should be considered as a first-line therapy for trauma patients in extremis. LEVEL OF EVIDENCE: Therapeutic, level III.

Indexed as

Vascular Access DevicesAdultEmergency Medical ServicesFemaleHumansInfusions, IntraosseousInfusions, IntravenousMaleProspective StudiesResuscitationShock, HemorrhagicSurvival RateUnited StatesVideo Recording

Identifiers

PMID29300281
PMCPMC5860964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.