Evidence map›Paper›PMID 29299997›Full record

ArticleeLife2018

Systemic and local cues drive neural stem cell niche remodelling during neurogenesis in

Pauline Spéder, Andrea H Brand

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Starve-Feed Cycles Direct Quiescence to Proliferation Transitions inbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Frontiers in cell and developmental biology · 2026
    Review
  8. Regulating glial morphogenesis: insights fromFrontiers in cell and developmental biology · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Beyond synapses: cytoplasmic connections in brain function and evolution.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  13. Review
  14. TheeLife · 2025
    Article
  15. Article
  16. Article
  17. ThebioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Pauline SpéderDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-2934-5841
Andrea H BrandDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-2089-6954
Centre National de la Recherche Scientifique · FRUniversity of Cambridge · GB

Funding

Cancer Research UK C6946/A14492Wellcome Trust
6 · The paper itself

Abstract

Successful neurogenesis requires adequate proliferation of neural stem cells (NSCs) and their progeny, followed by neuronal differentiation, maturation and survival. NSCs inhabit a complex cellular microenvironment, the niche, which influences their behaviour. To ensure sustained neurogenesis, niche cells must respond to extrinsic, environmental changes whilst fulfilling the intrinsic requirements of the neurogenic program and adapting their roles accordingly. However, very little is known about how different niche cells adjust their properties to such inputs. Here, we show that nutritional and NSC-derived signals induce the remodelling of

Indexed as

Cell DifferentiationCell ProliferationNeurogenesisAnimalsCell CommunicationDrosophilaImmunohistochemistryNeural Stem CellsNeurogliadevelopmental biologyD. melanogasterglianeural stem cellneurogenesisneuronnichestem cells

Identifiers

PMID29299997
PMCPMC5754201
OpenAlexW2781759314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.