Evidence map›Paper›PMID 29299948›Full record

Observational studyRenal failure2018

Assessing the influence of acute kidney injury on the mortality in patients with acute myocardial infarction: a clinical trail.

Yan-Bei Sun, Yuan Tao, Min Yang

Abstract readObservational Study
In one paragraph

Observational study in Renal failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  7. Review
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  14. Acute Kidney Injury and Fluid Overload in Pediatric Cardiac Surgery.Current treatment options in pediatrics · 2019
    Article
  15. Correlation of the ORBIT Score With 30-Day Mortality in Patients With ST-Segment Elevation Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yan-Bei Suna Department of Nephrology , The Affiliated Third Hospital of Soochow University , Changzhou , Jiangsu Province , China.
Yuan Taob Medical Record Room , The Affiliated Third Hospital of Soochow University , Changzhou , Jiangsu Province , China.
Min Yanga Department of Nephrology , The Affiliated Third Hospital of Soochow University , Changzhou , Jiangsu Province , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAcute kidney injury (AKI) increases the risk of death following acute myocardial infarction (AMI). In this current study, we tried to understand the role of newly KDIGO defined AKI in AMI-induced early and late mortality.

methodsWe retrospectively analyzed the clinical data of AMI patients (totaling 1371 cases) from the hospital's computer database. And AKI was defined based on the KDIGO criteria but GFR or urinary output assessment was not used. Subsequently, we compared the association of AKI with 30-day and 30-day to 5-year all-cause mortality, using multivariate COX regression analysis with two models.

resultsWe observed the development of AKI in 410 (29.9%) patients during the hospital stay. The 30-day and 30-day to 5-year mortality rates were 5.6% and 11.3%, respectively, in 1371 AMI patients. Further, adjusted Cox regression analysis based on model 1 revealed that AKI severity was an independent risk factor of 30-day mortality, while AKI Stage 3 was an independent predictor of 30-day to 5-year mortality. Adjusted Cox regression analysis based on model 2 revealed that normal baseline renal function with AKI and impaired renal function with AKI were independent risk factors of 30-day mortality, while normal baseline renal function with AKI and impaired renal function with AKI were identified to be independent predictors of 30-day to 5-year mortality.

conclusionsWhether the baseline renal function decreased or not, AKI strongly correlated with short- and long-term all-cause mortality in patients with AMI. Specifically, the short-term mortality of AMI patients increased with more severe AKI.

Indexed as

Models, BiologicalAcute Kidney InjuryAgedFemaleGlomerular Filtration RateHospitalizationHumansKidneyMaleMiddle AgedMyocardial InfarctionRetrospective StudiesRisk FactorsTime FactorsAcute kidney injuryacute myocardial infarctionbaseline GFRKDIGOmortality

Identifiers

PMID29299948
PMCPMC6014376

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.