ReviewThe world journal of men's health2018
Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment.
Review in The world journal of men's health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Discontinuation Rates of Tadalafil Alone and in Combination with a-Blockers in the Treatment of Male Lower Urinary Tract Symptoms with or without Coexisting Erectile Dysfunction: A Systematic Review and Meta-Analysis.International journal of clinical practice · 2022Pooled it
- Which of available selective serotonin reuptake inhibitors (SSRIs) is more effective in treatment of premature ejaculation? A randomized clinical trial.International braz j urol : official journal of the Brazilian Society of UrologyTrial
- Men with delayed ejaculation report lower sexual satisfaction and more depressive symptoms than those with premature ejaculation: findings from a cross-sectional study.International journal of impotence research · 2026Article
- Association of mandibular functional impairment and orofacial pain with subtypes of male sexual dysfunction: a cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2026Article
- Seminal vesicles - an overlooked pair of accessory glands in male sexual dysfunction: a narrative review.International journal of impotence research · 2025Review
- Abnormal grey matter in identifying primary intravaginal anejaculation patients from healthy controls: a voxel-based morphometry analysis.Sexual medicine · 2025Article
- Sympathetic hyperactivity in situational delayed ejaculation (intravaginal anejaculation phenotype): a neurophysiological case-control study.Translational andrology and urology · 2025Article
- A population analysis of delayed ejaculation using a claims database: characteristics and national trends in prevalence, incidence, and pharmacotherapy.International journal of impotence research · 2025Article
- Altered regional brain activity and functional connectivity in primary intravaginal anejaculation patients revealed by resting-state fMRI.Asian journal of andrology · 2024Article
- Male delayed orgasm and anorgasmia: a practical guide for sexual medicine providers.International journal of impotence research · 2024Review
- A Scoping Review of the Influence of Mindfulness on Men's Sexual Activity.International journal of environmental research and public health · 2023Article
- Premature ejaculation among Chinese urban men: prevalence and correlates.Sexual medicine · 2023Article
- Delayed Ejaculation After Lumbar Spine Surgery: A Claims Database Analysis.Global spine journal · 2022Article
- Review
- Ejaculatory dysfunction in men with diabetes mellitus.World journal of diabetes · 2021Review
- Delayed Ejaculation Due to Improper Male Condom Size: A Case Report.Sexual medicine · 2021Article
- Male Ejaculatory Endophenotypes: Revealing Internal Inconsistencies of the Concept in Heterosexual Copulating Rats.Frontiers in behavioral neuroscience · 2020Article
- Treatment persistence with a fixed-dose combination of tadalafil (5 mg) and tamsulosin (0.4 mg) and reasons for early discontinuation in patients with benign prostatic hyperplasia and erectile dysfunction.Investigative and clinical urology · 2020Observational
- The Potential Associations of Pornography Use with Sexual Dysfunctions: An Integrative Literature Review of Observational Studies.Journal of clinical medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase. We combined "delayed ejaculation," "retarded ejaculation," "inhibited ejaculation," or "anejaculation" as Medical Subject Headings (MeSH) terms or keywords with "epidemiology," "etiology," "pathophysiology," "clinical assessment," "diagnosis," or "treatment." Relevant sexual medicine textbooks were searched as well. The literature suggests that the pathophysiology of DE/AE is multifactorial, including both organic and psychosocial factors. Despite the many publications on this condition, the exact pathogenesis is not yet known. There is currently no single gold standard for diagnosing DE/AE, as operationalized criteria do not exist. The history is the key to the diagnosis. Treatment should be cause-specific. There are many approaches to treatment planning, including various psychological interventions, pharmacotherapy, and specific treatments for infertile men. An approved form of drug therapy does not exist. A number of approaches can be employed for infertile men, including the collection of nocturnal emissions, prostatic massage, prostatic urethra catheterization, penile vibratory stimulation, probe electroejaculation, sperm retrieval by aspiration from either the vas deferens or the epididymis, and testicular sperm extraction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.