Evidence map›Paper›PMID 29299826›Full record

ArticleForensic science, medicine, and pathology2018

Differentiation of antemortem pulmonary thromboembolism and postmortem clot with unenhanced MRI: a case report.

Ingo von Both, Silvio Giancarlo Bruni, Jayantha C Herath

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Forensic science, medicine, and pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cadaver clots: a systematic review of the literature.Forensic science, medicine, and pathology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ingo von BothOntario Forensic Pathology Service, Forensic Services and Coroner's Complex, 25 Morton Shulman Avenue, Toronto, Ontario, M3M 0B1, Canada. ingo.vonboth@ontario.ca.
Silvio Giancarlo BruniDepartment of Medical Imaging, University of Toronto, 2707-55 Bremner Boulevard, Toronto, Ontario, M5J 0A6, Canada.
Jayantha C HerathOntario Forensic Pathology Service, Forensic Services and Coroner's Complex, 25 Morton Shulman Avenue, Toronto, Ontario, M3M 0B1, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 39-year-old woman who died of fulminant pulmonary thromboembolism (PE). Autopsy showed classical findings of fulminant PE with occlusion of the bilateral main stem pulmonary arteries. Ancillary testing revealed inherited thrombophilia (Prothrombin 20,210 G > A and MTHFR 677 C > T mutation). Pre-autopsy postmortem computed tomography was used to test whether virtual imaging studies alone (virtual autopsy) would be sufficient to detect PE. Our studies show that computed tomography (CT) can differentiate antemortem clots from a postmortem clot in certain cases, particularly when combined with magnetic resonance imaging (MRI), which is superior in the assessment of soft tissue. We show that postmortem CT and MRI can aid in the diagnosis of pulmonary embolism by virtual autopsy, especially when used in conjunction.

Indexed as

Magnetic Resonance ImagingAdultFemaleHumansPulmonary ArteryPulmonary EmbolismThrombophiliaThrombosisTomography, X-Ray ComputedAntemortem clotMagnetic resonance imagingMRIPathologyPostmortem clotPulmonary thromboembolism

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.