Evidence map›Paper›PMID 29299824›Full record

ArticleInternational urology and nephrology2018

The value of synchro-cystourethrometry for evaluating the relationship between urethral instability and overactive bladder.

Chaoyang Hua, Yibo Wen, Yan Zhang, Quande Feng, Xiangfei He, Yunlong Li, Junwei Wu, Jinjin Feng, Stuart B Bauer, Jianguo Wen

Abstract read
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In one paragraph

Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Chaoyang HuaDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yibo WenDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yan ZhangDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Quande FengDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Xiangfei HeDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yunlong LiDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Junwei WuDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Jinjin FengDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Stuart B BauerDepartment of Urology, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02215, USA.
Jianguo WenDepartment of Urology, Pediatric Urodynamic Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. wenjg@hotmail.com.ORCID http://orcid.org/0000-0003-0952-118X
Henan Institute of Education · CNFirst Affiliated Hospital of Zhengzhou University · CNBoston Children's Hospital · USZhengzhou University · CN

Funding

National Natural Science Foundation of China (CN) 81670689
6 · The paper itself

Abstract

purposeTo investigate the correlation between urethral instability (URI) and overactive bladder (OAB) in children.

methodsWe retrospectively investigated 126 children with OAB and 36 children without OAB using synchro-cystourethrometry. The prevalence of detrusor overactivity (DO) and URI, and the diagnostic sensitivity of DO alone and DO combined with URI, was compared. The OAB children with URI voluntarily received transcutaneous electrical pudendal nerve stimulation with anisodamine (stimulation group, SG) or anisodamine alone (non-stimulation group, NSG). The effectiveness of treatment was evaluated. Average voided volume (AVV), maximum voided volume (MVV), and number of voids per day (NV) were collected and analyzed.

resultsIn OAB children, the prevalence of DO and URI was 51.6 and 32.5%, respectively. The prevalence of URI was 5.6% in controls. The prevalence of URI was significantly higher in OAB children. The diagnostic sensitivity and Youden index of DO combined with URI were higher than DO alone. In SG, 45.7% of children were cured, with a ≥ 50% improvement rate of 82.9%, while no child was cured, with a ≥ 50% improvement rate of 36.8% in NSG. A significant increase in AVV and MVV together, with a decrease in NV, was seen in SG. There was a significant difference in visual analogue scale values between SG and NSG (P < 0.01).

conclusionsUrethral instability plays an essential role in the pathogenesis and progression of OAB in children. Synchro-cystourethrometry is a useful urodynamic technology to precisely diagnose OAB, and transcutaneous electrical pudendal nerve stimulation may be an effective treatment for OAB children induced by URI.

Indexed as

Transcutaneous Electric Nerve StimulationAdrenergic alpha-AgonistsChildCombined Modality TherapyFemaleHumansMalePudendal NerveRetrospective StudiesSolanaceous AlkaloidsUrethral DiseasesUrinary BladderUrinary Bladder, OveractiveUrinationUrodynamicsAdrenergic alpha-AgonistsanisodamineSolanaceous AlkaloidsElectrical nerve stimulationOveractive bladderPediatricsUrethral instabilityUrodynamics

Identifiers

PMID29299824
OpenAlexW2781711847

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.