ArticlePflugers Archiv : European journal of physiology2018
Segmental differences in the non-neuronal cholinergic system in rat caecum.
Article in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Molecular Diversity and Functional Implications of Mammalian Choline Acetyltransferases in Neuronal and Non-Neuronal Cells.International journal of molecular sciences · 2026Review
- Inflammation and Organic Cation Transporters Novel (OCTNs).Biomolecules · 2024Review
- Loss of ERβ in Aging LXRαβ Knockout Mice Leads to Colitis.International journal of molecular sciences · 2023Article
- Article
- Evidence for tetrodotoxin-resistant spontaneous myogenic contractions of mouse isolated stomach that are dependent on acetylcholine.British journal of pharmacology · 2022Article
- News in caecal signalling: the role of propionate in microbial-epithelial crosstalk.Pflugers Archiv : European journal of physiology · 2021Article
- The role of HCOPflugers Archiv : European journal of physiology · 2021Article
- Unravelling the secrets of the caecum.Pflugers Archiv : European journal of physiology · 2019Article
- Segmental differences in ion transport in rat cecum.Pflugers Archiv : European journal of physiology · 2019Article
- Robustness of the non-neuronal cholinergic system in rat large intestine against luminal challenges.Pflugers Archiv : European journal of physiology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acetylcholine is not only a neurotransmitter but is also produced by several non-neuronal cell types with barrier or defence function. One of the non-neuronal tissues with expression of the key enzyme for production of acetylcholine, the choline acetyltransferase (ChAT), is the colonic surface epithelium, which releases acetylcholine after contact with the short-chain fatty acid propionate produced physiologically in the colonic lumen during the microbial fermentation of carbohydrates. Despite the fact that the caecum is the largest fermentation chamber in non-ruminant mammals, nothing is known about the expression and function of a non-neuronal cholinergic system in this part of the large intestine, which was addressed in the present study. In Ussing chamber experiments, propionate induced a concentration-dependent Cl
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Registered trials
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