ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018
The incidence of brainstem primitive neuroectodermal tumors of childhood based on SEER data.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Contemporary Management of Pediatric Brainstem Tumors.Advances and technical standards in neurosurgery · 2024Review
- Giant primitive neuroectodermal pelvic tumour: a case report and literature review.The Journal of international medical research · 2020Review
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Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
Abstract
purposeIncidence of BS primitive neuroectodermal tumors (BS-PNET) in children is not reported to date. Our main objectives were to estimate the incidence and report the outcome of BS-PNET in children.
methodsData were collected using the Surveillance Epidemiology and End Results cancer registry.
resultsFrom 1973 to 2013, we identified 83 pediatric patients (aged 0-21 years). Patients were divided into two age groups (0-3 years and 4-21 years). Median overall survival was 53 months. Patients in the older age group had a significant survival advantage (P < 0.001), as did those who received three modalities of therapy (surgery, chemotherapy, and radiation therapy) (P < 0.001) and patients with gross or subtotal tumor resection (P < 0.001).
conclusionsThis study presents the first estimate of incidence and the largest cohort of pediatric BS-PNETs to date. A high index of suspicion of BS-PNET in similar cases is crucial for diagnosis, treatment, and outcome.
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