Evidence map›Paper›PMID 29299662›Full record

ArticleWorld journal of urology2018

The association between intraoperative fluid intake and postoperative complications in patients undergoing radical cystectomy with an enhanced recovery protocol.

Soroush T Bazargani, Saum Ghodoussipour, Beverly Tse, Gus Miranda, Jie Cai, Anne Schuckman, Siamak Daneshmand, Hooman Djaladat

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Soroush T BazarganiInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA.
Saum GhodoussipourInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA.
Beverly TseStritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Gus MirandaInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA.
Jie CaiInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA.
Anne SchuckmanInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA.
Siamak DaneshmandInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA.
Hooman DjaladatInstitute of Urology, USC/Norris Comprehensive Cancer Center, USC, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA, 90089, USA. djaladat@med.usc.edu.
USC Norris Comprehensive Cancer Center · USLoyola University Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the association between intraoperative fluid intake and postoperative complications in patients who underwent radical cystectomy (RC) for bladder cancer with an enhanced recovery protocol.

methods287 patients underwent open RC with enhanced recovery protocol (ERAS) from 2012 to 2016. 107 were excluded; non-urothelial (30), palliative (37), had adjunct procedures or not-consented (40). We prospectively evaluated intraoperative fluid intake (crystalloid, colloid and blood) and correlated with length of stay, 30- and 90-day complications.

results180 patients enrolled into the study with median age of 70 years (78% male). 71% underwent orthotopic diversion. Median intraoperative crystalloid and colloid intake were 4000 and 500 cc, respectively. Nineteen percent of patients received blood transfusion. Median length of stay was 4 days. The overall 30- and 90-day complication rates were 59 and 75%, respectively. Multivariate logistic regressions controlling for a subset of clinically relevant variables showed no significant association between intraoperative fluid intake and complications at 30 or 90 days (p = 0.88 and 0.62, respectively). A multivariable linear regression similarly showed no association between total intraoperative fluid intake and length of stay (p = 0.099).

conclusionHigher intraoperative fluid intake was not found to independently increase the complication rate following radical cystectomy. Larger studies and prospective trials are needed to determine if fluid optimization may play a role in decreasing morbidity after this major surgery.

Indexed as

AdultAgedAged, 80 and overBlood TransfusionCarcinoma, Transitional CellClinical ProtocolsColloidsCrystalloid SolutionsCystectomyFemaleFluid TherapyHumansIntraoperative CareIsotonic SolutionsLength of StayLinear ModelsColloidsCrystalloid SolutionsIsotonic SolutionsBladder cancerComplicationsCystectomyEnhanced recoveryFluid therapy

Identifiers

PMID29299662
OpenAlexW2782274867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.