Evidence map›Paper›PMID 29299645›Full record

ArticleWorld journal of surgery2018

Transcutaneous Laryngeal Ultrasonography for Laryngeal Immobility Diagnosis in Patients with Voice Disorders After Thyroid/Parathyroid Surgery.

Diane S Lazard, Héloïse Bergeret-Cassagne, Muriel Lefort, Laurence Leenhardt, Gilles Russ, Frédérique Frouin, Christophe Trésallet

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03976011 (Validation and Optimization Methods for a Quantitative Characterization of Motion Abnormalities of the Larynx With Echography), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03976011 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Validation and Optimization Methods for a Quantitative Characterization of Motion Abnormalities of the Larynx With Echography

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2019 to 2024Enrolled500ConditionsRecurrent Laryngeal Nerve Palsy, Postoperative DysphoniaArmsTranscutaneous Laryngeal Ultrasonography
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Ultrasonographic measurement of glottal area: A potential biomarker study in young Normophonic adults.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  2. Observational
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  5. Normative data for certain vocal fold biomarkers among young normophonic adults using ultrasonography.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Diane S LazardDepartment of General, Visceral and Endocrine Surgery, Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne Universités Pierre et Marie Curie (Paris 6), 47-83, Boulevard de l'Hôpital, 75013, Paris, France.
Héloïse Bergeret-CassagneDepartment of General, Visceral and Endocrine Surgery, Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne Universités Pierre et Marie Curie (Paris 6), 47-83, Boulevard de l'Hôpital, 75013, Paris, France.
Muriel LefortLaboratoire d'Imagerie Biomédicale (LIB), Inserm, CNRS, Sorbonne Universités Pierre et Marie Curie (Paris 6), Paris, France.
Laurence LeenhardtLaboratoire d'Imagerie Biomédicale (LIB), Inserm, CNRS, Sorbonne Universités Pierre et Marie Curie (Paris 6), Paris, France.
Gilles RussDepartment of endocrinology, Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne Universités Pierre et Marie Curie (Paris 6), Paris, France.
Frédérique FrouinLaboratoire Imagerie Moléculaire in Vivo (IMIV), Inserm, CEA, Univ. Paris-Sud, CNRS, Université Paris-Saclay, Orsay, France.
Christophe TrésalletDepartment of General, Visceral and Endocrine Surgery, Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne Universités Pierre et Marie Curie (Paris 6), 47-83, Boulevard de l'Hôpital, 75013, Paris, France. christophe.tresallet@aphp.fr.
Sorbonne Université · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscutaneous laryngeal ultrasonography (TLUS) was recently developed to assess recurrent nerve palsy after thyroid/parathyroid surgery, with variable rates of efficiency. The aim of the current study was to evaluate this technique using subjective estimation and post-processing quantitative data.

methodsFifty subjects presenting with a recurrent nerve palsy and 50 "controls" presenting with voice, swallowing, or breathing disorders following thyroid/parathyroid surgery were prospectively included. All of them underwent a flexible laryngoscopy, considered the gold standard, and a ten-second TLUS clip within the 10 days following surgery. In addition to the subjective interpretation of vocal fold motion, two quantitative criteria taking into account motion symmetry (symmetry index, SI) and amplitude (mobility index) of the two hemi-larynges were defined on TLUS acquisitions in adduction and abduction.

resultsThe subjective interpretation provided a sensitivity of 100% and a specificity of 96%, compared to the gold standard. The quantitative criteria provided a sensitivity and specificity of both 82%, when based on SI solely. When combining SI and mobility index, the sensitivity reached 94%, but the specificity fell to 66%.

conclusionsVisual assessment of recurrent nerve palsy using TLUS after thyroid/parathyroid surgery appeared a high sensitive and specific test compared to flexible laryngoscopy. Quantitative criteria are promising and need to be refined to better describe the whole TLUS video clip.

Indexed as

AdultAgedFemaleHumansLarynxMaleMiddle AgedParathyroid GlandsSensitivity and SpecificityThyroid GlandUltrasonographyVocal Cord ParalysisVoice Disorders

Identifiers

PMID29299645
OpenAlexW2782464771

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.