ArticleLaryngoscope investigative otolaryngology2017
Head and neck paragangliomas: A two-decade institutional experience and algorithm for management.
Article in Laryngoscope investigative otolaryngology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Current evidence and future perspectives in the treatment of head and neck vagal paragangliomas: a systematic review.Systematic reviews · 2026Pooled it
- Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis.Neurosurgical review · 2021Pooled it
- Hypertensive crisis during embolization unveils occult catecholamine-secreting glomus jugulare tumor: A case report and management protocol.Experimental and therapeutic medicine · 2026Article
- Rates of Hereditary Paraganglioma Syndromes and Secretory Head and Neck Paragangliomas: A Single-Institution Experience.Journal of neurological surgery. Part B, Skull base · 2026Article
- Clinical and genetic characteristics of head and neck paragangliomas from China featuring Sino-European comparisons.Journal of the Endocrine Society · 2026Article
- "Clinicopathological profile of paragangliomas: A 5-Year retrospective analysis from a single tertiary Centre".Diagnostic pathology · 2026Article
- Vagus Nerve Schwannoma: A Case Report and Literature Review.Clinical case reports · 2025Article
- Pheochromocytomas and Paragangliomas-Current Management.Cancers · 2025Review
- Management of bilateral head and neck paragangliomas at a single-institution across four decades.Head & neck · 2025Article
- Multidisciplinary Management of Lateral Skull Base Paragangliomas: A 20-Year Experience.Journal of neurological surgery. Part B, Skull base · 2024Article
- Head and Neck Paragangliomas: 16-year Single-center Experience and Mini Review on Diagnosis, Treatment, and Follow-up.Medeniyet medical journal · 2024Article
- Thyroid Paraganglioma: A Rare Manifestation of Paraganglioma Syndrome Associated With Pathogenic Variant inJCEM case reports · 2024Article
- Tumor volume changes after stereotactic, hypofractionated and conventional radiotherapy in paragangliomas of head and neck.Cancer medicine · 2024Article
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- Molecular pathology of endocrine gland tumors: genetic alterations and clinicopathologic relevance.Virchows Archiv : an international journal of pathology · 2024Review
- Jugular Foramen Paragangliomas.Advances and technical standards in neurosurgery · 2024Article
- An Update on Temporal Bone Paragangliomas.Current treatment options in oncology · 2023Review
- Primary intra-abdominal paraganglioma: A case report.World journal of clinical cases · 2023Article
- Precise differentiation between jugular foramen paragangliomas and metastases: utility of diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging.Neuroradiology · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Objectives: Paragangliomas of the head and neck and cranial base are typically benign, slow-growing tumors arising within the jugular foramen, middle ear, carotid bifurcation, or vagus nerve proper. The objective of this study was to provide a comprehensive characterization of our institutional experience with clinical management of these tumors and posit an algorithm for diagnostic evaluation and treatment. Methods: This was a retrospective cohort study of patients undergoing treatment for paragangliomas of the head and neck and cranial base at our institution from 2000-2017. Data on tumor location, catecholamine levels, and specific imaging modalities employed in diagnostic work-up, pre-treatment cranial nerve palsy, treatment modality, utilization of preoperative angiographic embolization, complications of treatment, tumor control and recurrence, and hereditary status (ie, succinate dehydrogenase mutations) were collected and summarized. Results: The mean (SD) age of our cohort was 51.8 (±16.1) years with 123 (63.4%) female patients and 71 (36.6%) male patients. Catecholamine-secreting lesions were found in nine (4.6%) patients. Fifty-one patients underwent genetic testing, with mutations identified in 43 (20 Conclusion: An algorithmic approach to clinical management of these tumors, derived from our longitudinal institutional experience and current empiric evidence, may assist otolaryngologists, radiation oncologists, and geneticists in the care of these complex neoplasms. Level of Evidence: 4.
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