ArticleJournal of comorbidity2017
Chronic migraine, comorbidity, and socioeconomic deprivation: cross-sectional analysis of a large nationally representative primary care database.
Article in Journal of comorbidity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Understanding the nature of psychiatric comorbidity in migraine: a systematic review focused on interactions and treatment implications.The journal of headache and pain · 2019Pooled it
- Eptinezumab in episodic migraine: A randomized, double-blind, placebo-controlled study (PROMISE-1).Cephalalgia : an international journal of headache · 2020Trial
- Health inequalities in outpatient neurological conditions across a large UK urban population: a retrospective observational study using automated coding.BMJ neurology open · 2026Article
- The effect of greater occipital nerve block on amplification of somatic symptoms and anxiety and depression levels in chronic migraine.Acta neurologica Belgica · 2024Article
- Acute treatment of migraine: quantifying the unmet need through real-world data in Italy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- CGRP Antagonism and Ketogenic Diet in the Treatment of Migraine.Medicina (Kaunas, Lithuania) · 2024Review
- Systematic review and meta-analysis of calculating degree of comorbidity of irritable bowel syndrome with migraine.BioPsychoSocial medicine · 2023Article
- Revisiting Migraine: The Evolving Pathophysiology and the Expanding Management Armamentarium.Cureus · 2023Review
- Stress and Its Correlates in Migraine-Headache Patients with a Family History of Migraine.Behavioral sciences (Basel, Switzerland) · 2022Article
- Uterine fibroids and incidence of depression, anxiety and self-directed violence: a cohort study.Journal of epidemiology and community health · 2022Article
- The eptinezumab:CGRP complex structure - the role of conformational changes in binding stabilization.Bioengineered · 2021Article
- Depression, Anxiety, and Self-Directed Violence in Women With Endometriosis: A Retrospective Matched-Cohort Study.American journal of epidemiology · 2021Article
- Comorbid and co-occurring conditions in migraine and associated risk of increasing headache pain intensity and headache frequency: results of the migraine in America symptoms and treatment (MAST) study.The journal of headache and pain · 2020Article
- Content Validity of HIT-6 as a Measure of Headache Impact in People With Migraine: A Narrative Review.Headache · 2020Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundChronic migraine is common but there is limited knowledge on associated comorbidities.
objectivesTo examine mental and physical comorbidities in chronic migraine and the influence of socioeconomic status in a large, nationally representative dataset.
designAnalysis of cross-sectional primary healthcare data from 1,468,404 adults in Scotland. Chronic migraine, 31 other physical conditions, and seven mental health conditions we examined. Prevalence rates were standardized by age groups, sex, and socioeconomic deprivation, and adjusted odds ratio (aOR) and 95% confidence intervals (CI) calculated for those with chronic migraine compared with those without.
resultsChronic migraine patients had more conditions, with the biggest difference found for five or more conditions (chronic migraine 11.7% vs. controls 4.9%; aOR 3.00; 95% CI 2.78-3.22). Twenty-five of the 31 physical conditions were significantly more prevalent in the chronic migraine group. The biggest difference was for chronic pain (aOR 4.33; 95% CI 4.12-4.55). For mental health conditions, the biggest differences were for anxiety (aOR 2.95; 95% CI 2.76-31.5) and depression (aOR 2.94; 95% CI 2.81-3.08). Increasing deprivation was associated with more severe and complex comorbidity (five or more conditions), and with more combined mental and physical comorbidity in the chronic migraine group.
conclusionsIn a large nationally representative sample in primary care, comorbidity was most common in those with chronic migraine compared with standardized controls, and this was exacerbated by living in areas of higher deprivation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.