Evidence map›Paper›PMID 29299432›Full record

ArticleAvicenna journal of phytomedicine

Effects

Aditya Jielella Reddy, Ashok Kumar Dubey, Shailendra Handu, Manocha Sachin, Pramod Kumari Mediratta, Qazi Ahmed Mushtaq

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aditya Jielella ReddyDepartment of Pharmacology, SMS&R, Sharda University, Gr. Noida, NCR, India.
Ashok Kumar DubeyDepartment of Pharmacology, SMS&R, Sharda University, Gr. Noida, NCR, India.
Shailendra HanduDepartment of Pharmacology, SMS&R, Sharda University, Gr. Noida, NCR, India.
Manocha SachinDepartment of Pharmacology, SMS&R, Sharda University, Gr. Noida, NCR, India.
Pramod Kumari MedirattaDepartment of Pharmacology, SMS&R, Sharda University, Gr. Noida, NCR, India.
Qazi Ahmed MushtaqDepartment of Pharmacology, SMS&R, Sharda University, Gr. Noida, NCR, India.
Sharda University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe MATERIAL AND

methodsElevated Plus Maze method and locomotor monitoring by photoactometer were used. Animals were divided into five different groups (n=6/group). The vehicle, standard and the experimental groups were given distilled water (10 ml/kg), diazepam (1 mg /kg intraperitoneally) and incremental doses of 25, 50 and 100 mg/kg of MSSE, respectively, prior to the experiment. The standard group received diazepam.

resultsThe number of open arm entries and the duration of time spent in the open arms in the MSSE-treated groups increased significantly in a dose-dependent manner as compared to that of control group. The duration of time spent in closed arms in the MSSE-treated groups decreased significantly in a dose-dependent manner as compared to that of the control group. MSSE also decreased the locomotor activity significantly at all three test doses.

conclusionThe results of this study suggest an anxiolytic activity for MSSE, which make it a potential natural compound for treatment of anxiety disorders.

Indexed as

AnxietyElevated plus mazeMiceMusa sapientumOxidative stress

Identifiers

PMID29299432
PMCPMC5745533
OpenAlexW2621710524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.