ReviewJournal of gastrointestinal oncology2017
Management of liver metastases from gastrointestinal stromal tumors: where do we stand?
Review in Journal of gastrointestinal oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Efficacy and safety of CalliSpheres drug-eluting bead transarterial chemoembolization for unresectable gastrointestinal stromal tumor liver metastases after failure of targeted therapy: a multicenter retrospective study.Frontiers in oncology · 2026Article
- Effects of surgical management for gastrointestinal stromal tumor patients with liver metastasis on survival outcomes.Frontiers in oncology · 2024Article
- Defining the surgical management for non-colorectal liver metastases.Langenbeck's archives of surgery · 2023Article
- Parenchyma-Sparing Liver Resection or Regenerative Liver Surgery: Which Way to Go?Medicina (Kaunas, Lithuania) · 2022Review
- Rectal gastrointestinal stromal tumor with metachronous liver metastasis demonstrated no relapse after multidisciplinary team discussion and comprehensive treatment: a case report.Journal of gastrointestinal oncology · 2022Article
- Hepatic GIST metastases: an illustrative case series.BJR case reports · 2022Article
- Liver transplantation combined with tyrosine kinase inhibitors for the treatment of hepatic metastatic giant gastrointestinal stromal tumors: A case report and literature review.Frontiers in gastroenterology (Lausanne, Switzerland) · 2022Article
- Humeral metastasis as the only recurrence of a 5-year resected gastrointestinal stromal tumor: a case report.Journal of medical case reports · 2021Article
- Some Special Aspects of Liver Repair after Resection and Administration of Multipotent Stromal Cells in Experiment.Life (Basel, Switzerland) · 2021Article
- Prevalence, diagnosis, and treatment of primary hepatic gastrointestinal stromal tumors.World journal of gastroenterology · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recommended management of liver metastases (LM) from gastrointestinal stromal tumors (GISTs) disease consists of perioperative administration of tyrosine kinase inhibitors (TKIs) and surgical resection. The aim of our study was to investigate the efficacy of this therapeutic approach. Studies reporting outcomes for patients underwent liver resection from metastatic gastrointestinal stromal tumor (GIST) were overviewed. Eleven studies were included, which enrolled 240 patients with liver metastasis from GISTs. A median overall survival (OS) interval of 41.8 months was calculated while a median disease free interval of 17.9 [17-43] months following resection was also measured. Recurrences were recorded in 63 patients. Prognostic factors identified by the studies included surgical resection, R0 resection, age <55 years, clinical response to TKIs, pre- and postoperative administration of TKIs. The included studies highlight the importance of complete resection and the timing of resection, as well underline the importance of pre- and post-operative administration of TKIs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.