Evidence map›Paper›PMID 29299206›Full record

ArticleIranian journal of basic medical sciences2017

Therapeutic potential of

Davood Nasiry, Ali Reza Khalatbary, Hassan Ahmadvand

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Davood NasiryAnatomy Department, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Ali Reza KhalatbaryMolecular and Cell Biology Research Center, Department of Anatomy, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Hassan AhmadvandDepartment of Biochemistry, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mazandaran University of Medical Sciences · IRLorestan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). MATERIALS AND

methodsThe DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats received JRL or metformin after the onset of hyperglycemia. Histopathology and immunohistochemistry of apoptotic and inflammatory factors were assessed along with biochemical assessments of lipid peroxidation and antioxidant status.

resultsLipid peroxidation level and catalase activity significantly improved after JRL consumption (

conclusionJRL leaf extract exert protective effects against diabetic retinopathy.

Indexed as

AntioxidantApoptosisDiabetic retinopathyHyperglycemiaInflammationJuglans regia L. leaf

Identifiers

PMID29299206
PMCPMC5749363
OpenAlexW2763695258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.