Evidence map›Paper›PMID 29299190›Full record

ArticleAnnali di stomatologia

Evaluation of microbiota associated with Herpesviruses in active sites of generalized aggressive periodontitis.

Claudio Passariello, Pierangelo Gigola, Luca Testarelli, Monica Puttini, Serena Schippa, Stefano Petti

Open access · diamondAbstract read
In one paragraph

Article in Annali di stomatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Cancers · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Microbiome-mediated incapacitation of interferon lambda production in the oral mucosa.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Article
  10. The oralome and its dysbiosis: New insights into oral microbiome-host interactions.Computational and structural biotechnology journal · 2021
    Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Claudio PassarielloDepartment of Public Health and Infectious Diseases, " Sapienza" University of Rome, Rome, Italy.
Pierangelo GigolaDepartment of Medical-Surgical Specialties, Radiologic and Public Health Sciences University of Brescia, Brescia, Italy.
Luca TestarelliDepartment of Odontostomatologic and Maxillo-Facial Sciences, "Sapienza" University of Rome, Rome, Italy.
Monica PuttiniFree Practice in Dentistry, Genova, Italy.
Serena SchippaDepartment of Public Health and Infectious Diseases, " Sapienza" University of Rome, Rome, Italy.
Stefano PettiDepartment of Public Health and Infectious Diseases, " Sapienza" University of Rome, Rome, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe present study aimed to investigate microbial patterns associated with disease progression and coinfection by different Herpesviruses in generalized aggressive periodontitis (GAP).

methodsMicrobiological samples were obtained from active (AS) and non-active (n-AS) sites in 165 subjects affected by GAP and were analyzed for 40 bacterial species by the Checkerboard DNA-DNA Hybridization technique and for Herpes simplex 1 (HSV-1), Human Cytomegalovirus (CMV), and Epstein Bar virus (EBV) by PCR.Common Factor Analysis and Multiple Regression Analysis were applied to disclose specific microbial patterns associated with the three viruses.

resultsHerpesviruses were detected in 37.6% of subjects. Detection of each of the searched viruses was associated with specific patterns of subgingival biofilm in AS. Logistic regression analyses evidenced several virus/bacteria associations: i) EBV with

conclusionsMicrobiological data suggest that Herpesviruses are probably not mere spectators of disease progression and that specific patterns of subgingival plaque are correlated with the presence of different Herpesviruses.

Indexed as

disease progressiongeneralized aggressive periodontitisherpesvirusesmicrobiota

Identifiers

PMID29299190
PMCPMC5749375
OpenAlexW2796975474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.