Evidence map›Paper›PMID 29299147›Full record

ArticleOncotarget2017

Accelerated atherogenesis in completely ligated common carotid artery of apolipoprotein E-deficient mice.

Zhihui Chang, Chaoji Huangfu, Andrew T Grainger, Jingang Zhang, Qiyong Guo, Weibin Shi

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Preclinical techniques to investigate exercise training in vascular pathophysiology.American journal of physiology. Heart and circulatory physiology · 2021
    Pooled it
  2. Atherogenesis inCells · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zhihui ChangDepartment of Radiology & Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
Chaoji HuangfuDepartment of Radiology & Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
Andrew T GraingerBiochemistry & Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.
Jingang ZhangBeijing Key Laboratory of Blood Safety and Supply Technologies, Beijing Institute of Transfusion Medicine, Beijing, China.
Qiyong GuoDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang, China.
Weibin ShiDepartment of Radiology & Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
University of Virginia · USChina Medical University · CNGuangzhou Blood Center · CN

Funding

Genetic link between type 2 diabetes and atherosclerosisR01DK097120 · NIDDK · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2013 to 2016
$1.4M
H2 haplotype and atherosclerosisR21HL112281 · NHLBI · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2012 to 2013
$414k
NHLBI NIH HHS R21 HL112281NIDDK NIH HHS R01 DK097120
6 · The paper itself

Abstract

Complete ligation of the common carotid artery near its bifurcation induces neointimal formation due to smooth muscle cell proliferation in normolipidemic wild-type mice, but it was unknown what would happen to hyperlipidemic apolipoprotein E-deficient (Apoe

Indexed as

atherosclerosisfoam cellhyperlipidemiamiceneovessel

Identifiers

PMID29299147
PMCPMC5746382
OpenAlexW2770711371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.