Evidence map›Paper›PMID 29299033›Full record

ArticleCellular & molecular biology letters2017

The mechanism of (+) taxifolin's protective antioxidant effect for •OH-treated bone marrow-derived mesenchymal stem cells.

Xican Li, Hong Xie, Qian Jiang, Gang Wei, Lishan Lin, Changying Li, Xingmei Ou, Lichan Yang, Yulu Xie, Zhen Fu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cellular & molecular biology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xican Li *School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.ORCID 0000-0002-4358-3993
Hong Xie *School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Qian JiangSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Gang WeiSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Lishan LinSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Changying LiSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Xingmei OuSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Lichan YangSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Yulu XieSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuang East Road No. 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006 China.
Zhen FuSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006 China.
Yamei LiuSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006 China.
Dongfeng ChenThe Research Center of Integrative Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006 China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural dihydroflavonol (+) taxifolin was investigated for its protective effect on Fenton reagent-treated bone marrow-derived mesenchymal stem cells (bmMSCs). Various antioxidant assays were used to determine the possible mechanism. These included •OH-scavenging, 2-phenyl-4, 4, 5, 5-tetramethylimidazoline-1-oxyl-3-oxide radical-scavenging (PTIO•-scavenging), 1, 1-diphenyl-2-picryl-hydrazl radical-scavenging (DPPH•-scavenging), 2, 2'-azino-bis (3-ethylbenzo-thiazoline-6-sulfonic acid) radical-scavenging (ABTS

Indexed as

AntioxidantsBone Marrow CellsHydroxyl RadicalInhibitory Concentration 50Mesenchymal Stem CellsProtective AgentsQuercetinSpectrophotometry, UltravioletAntioxidantsHydroxyl RadicalProtective AgentsQuercetintaxifolinAntioxidant mechanismElectron transferFe2+ binding•OH damage(+) Taxifolin; bmMSCs

Identifiers

PMID29299033
PMCPMC5745628
OpenAlexW2780997153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.