ArticleNature communications2018
Role of outer surface probes for regulating ion gating of nanochannels.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Biosensing With Nanofluidics.Exploration (Beijing, China) · 2026Review
- Outer-surface charge modulation of photothermal diffusion voltage enables ultrasensitive sensing in nanofluidic membranes.Chemical science · 2026Article
- DNA-Decorated PET Nanochannels for Sensitive Biosensing.Biosensors · 2025Article
- Sub-femtomolar drug monitoring via co-calibration mechanism with nanoconfined DNA probes.Nature communications · 2025Article
- A dual-mode biosensor for microRNA detection based on DNA tetrahedron-gated nanochannels.Mikrochimica acta · 2025Article
- High-performance solid-state proton gating membranes based on two-dimensional hydrogen-bonded organic framework composites.Nature communications · 2025Article
- Precise control of transmembrane current via regulating bionic lipid membrane composition.Science advances · 2024Article
- A highly sensitive nanochannel device for the detection of SUMO1 peptides.Chemical science · 2023Article
- Solid-State Nanopore/Nanochannel Sensing of Single Entities.Topics in current chemistry (Cham) · 2023Review
- Structurally Different Yet Functionally Similar: Aptamers Specific for the Ebola Virus Soluble Glycoprotein and GP1,2 and Their Application in Electrochemical Sensing.International journal of molecular sciences · 2023Article
- Functional nucleic acid engineered double-barreled nanopores for measuring sodium to potassium ratio at single-cell level.Exploration (Beijing, China) · 2022Article
- Structure and dynamics of nanoconfined water and aqueous solutions.The European physical journal. E, Soft matter · 2021Review
- Biomimetic Nanocomposite Membranes with Ultrahigh Ion Selectivity for Osmotic Power Conversion.ACS central science · 2021Article
- Regional and functional division of functional elements of solid-state nanochannels for enhanced sensitivity and specificity of biosensing in complex matrices.Nature protocols · 2021Article
- Super-spreading on superamphiphilic micro-organized nanochannel anodic aluminum oxide surfaces for heat dissipation.iScience · 2021Article
- Towards explicit regulating-ion-transport: nanochannels with only function-elements at outer-surface.Nature communications · 2021Article
- Arene Substitution Design for Controlled Conformational Changes of Dibenzocycloocta-1,5-dienes.Journal of the American Chemical Society · 2020Article
- Nanocompartmentalization of the Nuclear Pore Lumen.Biophysical journal · 2020Article
- A highly selective and recyclable NO-responsive nanochannel based on a spiroring opening-closing reaction strategy.Nature communications · 2019Article
- Label free thrombin detection in presence of high concentration of albumin using an aptamer-functionalized nanoporous membrane.Biosensors & bioelectronics · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanochannels with functional elements have shown promise for DNA sequencing, single-molecule sensing, and ion gating. Ionic current measurement is currently a benchmark, but is focused solely on the contribution from nanochannels' inner-wall functional elements (NIWFE); the attributes of functional elements at nanochannels' outer surface (NOSFE) are nearly ignored, and remain elusive. Here we show that the role of NOSFE and NIWFE for ion gating can be distinguished by constructing DNA architectures using dual-current readout. The established molecular switches have continuously tunable and reversible ion-gating ability. We find that NOSFE exhibits negligible ion-gating behavior, but it can produce a synergistic effect in alliance with NIWFE. Moreover, the high-efficiency gating systems display more noticeable synergistic effect than the low-efficiency ones. We also reveal that the probe amount of NOSFE and NIWFE is almost equally distributed in our biomimetic nanochannels, which is potentially a premise for the synergistic ion-gating phenomena.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.