Evidence map›Paper›PMID 29298934›Full record

ArticleProceedings. Biological sciences2018

Evolutionary and structural analyses uncover a role for solvent interactions in the diversification of cocoonases in butterflies.

G Smith, J E Kelly, A Macias-Muñoz, C T Butts, R W Martin, A D Briscoe

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

G SmithDepartment of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697, USA gilbert.smith@bangor.ac.uk.
J E KellyDepartment of Chemistry, University of California, Irvine, CA 92697, USA.
A Macias-MuñozDepartment of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697, USA.
C T ButtsDepartment of Sociology, University of California, Irvine, CA 92697, USA.
R W MartinDepartment of Chemistry, University of California, Irvine, CA 92697, USA.
A D BriscoeDepartment of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-omic approaches promise to supply the power to detect genes underlying disease and fitness-related phenotypes. Optimal use of the resulting profusion of data requires detailed investigation of individual candidate genes, a challenging proposition. Here, we combine transcriptomic and genomic data with molecular modelling of candidate enzymes to characterize the evolutionary history and function of the serine protease cocoonase.

Indexed as

Evolution, MolecularAnimalsButterfliesCatalytic DomainGenes, InsectInsect ProteinsModels, MolecularPhylogenyPlant NectarPollenRNA, MessengerSerine ProteasesSubstrate SpecificityTranscriptomeInsect ProteinsPlant NectarRNA, MessengerSerine Proteasescocoonasegene duplicationHeliconiuspollen feedingserine protease

Identifiers

PMID29298934
PMCPMC5784194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.