ArticleNeurology2018
Racial disparities in refusal of stroke thrombolysis in Chicago.
Article in Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06094478 (Implementation of a Stroke Protocol for Emergency Evaluation and Disposition), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study.Journal of the American Heart Association · 2024Article
- Racial Impact on Inpatient Stroke Quality of Care in Two Community Hospitals.Journal of clinical medicine · 2023Article
- Black Americans have worse stroke outcome compared with non-Hispanic whites.Journal of the National Medical Association · 2023Article
- Racial and Ethnic Disparities in Stroke Reperfusion Therapy in the USA.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Utilizing Implementation Science to Bridge Cerebrovascular Health Disparities: a Local to Global Perspective.Current neurology and neuroscience reports · 2022Review
- Article
- Contemporary Trends in the Treatment of Mild Ischemic Stroke with Intravenous Thrombolysis: Paul Coverdell National Acute Stroke Program.Cerebrovascular diseases (Basel, Switzerland) · 2022Article
- Acute Ischemic Stroke Interventions in the United States and Racial, Socioeconomic, and Geographic Disparities.Neurology · 2021Article
- Thrombolytic Refusal Over Telestroke.Neurology. Clinical practice · 2021Article
- Article
- Understanding determinants of acute stroke thrombolysis using the tailored implementation for chronic diseases framework: a qualitative study.BMC health services research · 2019Article
- Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo evaluate race differences in tissue plasminogen activator (tPA) refusal among eligible patients with acute ischemic stroke (AIS) in Chicago.
methodsUsing the Get With The Guidelines-Stroke registry data from 15 primary stroke centers between January 2013 and June 2015, we performed a retrospective analysis of patients with AIS presenting to the emergency department within 4.5 hours from symptom onset. Patient or proxy refusal was captured as a reason for nonadministration of tPA to eligible patients in the registry. We assessed whether tPA refusal differed by race using logistic regression.
resultsAmong 704 tPA-eligible patients with AIS, tPA was administered to 86.2% (black race, 82.5% vs nonblack race, 89.5%;
conclusionsAmong tPA-eligible patients with AIS in Chicago, over 7% refused tPA. Refusal was more common in black patients and accounted for the apparent lower rates of tPA use in black vs nonblack patients. Further research is needed to understand barriers to consent and overcome race-ethnic disparities in tPA treatment for AIS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.