Evidence map›Paper›PMID 29298843›Full record

ArticleEndocrine connections2018

NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features.

Catarina Tavares, Maria João Coelho, Catarina Eloy, Miguel Melo, Adriana Gaspar da Rocha, Ana Pestana, Rui Batista, Luciana Bueno Ferreira, Elisabete Rios, Samia Selmi-Ruby and 4 more

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. The effect ofFrontiers in endocrinology · 2025
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  12. CouldDiagnostics (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Catarina TavaresInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Maria João CoelhoInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Catarina EloyInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Miguel MeloInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Adriana Gaspar da RochaInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Ana PestanaInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Rui BatistaInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Luciana Bueno FerreiraInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Elisabete RiosInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Samia Selmi-RubyInserm UMR-S1052CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Bruno CavadasInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Luísa PereiraInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Manuel Sobrinho SimõesInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal.
Paula SoaresInstituto de Investigação e Inovação em Saúde (i3S)Porto, Portugal psoares@ipatimup.pt.
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTUniversidade do Porto · PTCentre de Recherche en Cancérologie de Lyon · FRUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer therapy is based on surgery followed by radioiodine treatment. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS) (codified by the

Indexed as

cancerimmunohistochemistryNISSLC5A5thyroid

Identifiers

PMID29298843
PMCPMC5754505
OpenAlexW2782286604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.