Evidence map›Paper›PMID 29298835›Full record

ArticleThe Plant cell2018

Histone Deacetylases SRT1 and SRT2 Interact with ENAP1 to Mediate Ethylene-Induced Transcriptional Repression.

Fan Zhang, Likai Wang, Eun Esther Ko, Kevin Shao, Hong Qiao

Open access · hybridAbstract read
In one paragraph

Article in The Plant cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 108 citations in OpenAlex.

  1. Epigenetic regulation and ROS signaling in plant stress adaptation: an integrated framework.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
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  4. The miR172a-ERF416/413 module regulates soybean seed traits.Journal of integrative plant biology · 2025
    Article
  5. Article
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  7. Article
  8. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. How chromatin senses plant hormones.Current opinion in plant biology · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fan ZhangInstitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712.
Likai WangInstitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712.
Eun Esther KoInstitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712.
Kevin ShaoInstitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712.
Hong QiaoInstitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712 hqiao@austin.utexas.edu.ORCID 0000-0003-3359-1962
The University of Texas at Austin · US

Funding

Molecular mechanisms of interplay between ethylene signaling and chromatin regulation in ArabidopsisR01GM115879 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI QIAO, HONG · 2015 to 2023
$2.9M
NIGMS NIH HHS R01 GM115879
6 · The paper itself

Abstract

Ethylene plays pleiotropic roles in plant growth, plant development, and stress responses. Although the effects of ethylene on plants are well documented, little is known about molecular-level events that result in transcriptional repression during the ethylene response. In this study, we found that two histone deacetylases, SRT1 and SRT2, interact with ENAP1, which associates with EIN2 in the nucleus. Genetic and transcriptome analyses revealed that SRT1 and SRT2 are required for negative regulation of certain ethylene-responsive genes. The acetylation of HISTONE3 at K9 (H3K9Ac) is specifically regulated by SRT1 and SRT2 in ethylene-repressed genes. In addition, the

Indexed as

Transcription, GeneticAcetylationArabidopsisArabidopsis ProteinsCarrier ProteinsEthylenesGene Expression Regulation, PlantGenes, PlantHistonesLysineMutationPhenotypeProtein BindingSaccharomyces cerevisiaeSilent Information Regulator Proteins, Saccharomyces cerevisiaeSirtuin 2Arabidopsis ProteinsCarrier ProteinsethyleneEthylenesHistonesLysineSilent Information Regulator Proteins, Saccharomyces cerevisiaeSIR2 protein, S cerevisiaeSirtuin 2SirtuinsSRT1 protein, ArabidopsisSRT2 protein, ArabidopsisTranscription FactorsVFP3 protein, Arabidopsis

Identifiers

PMID29298835
PMCPMC5810571
OpenAlexW2781609043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.