Evidence map›Paper›PMID 29298340›Full record

ArticlePloS one2018

The association between a body shape index and cardiovascular risk in overweight and obese children and adolescents.

Chiara Mameli, Nir Y Krakauer, Jesse C Krakauer, Alessandra Bosetti, Chiara Matilde Ferrari, Norma Moiana, Laura Schneider, Barbara Borsani, Teresa Genoni, Gianvincenzo Zuccotti

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Associations of Butyrylcholinesterase Activity and Lipid-Related Indices with Obesity in Thai Children.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chiara MameliDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.ORCID 0000-0002-6768-3411
Nir Y KrakauerDepartment of Civil Engineering, The City College of New York, New York, NY, United States of America.
Jesse C KrakauerMetro Detroit Diabetes and Endocrinology, Southfield, MI, United States of America.
Alessandra BosettiDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.
Chiara Matilde FerrariDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.
Norma MoianaDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.
Laura SchneiderDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.
Barbara BorsaniDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.
Teresa GenoniDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.
Gianvincenzo ZuccottiDepartment of Pediatrics, V. Buzzi Children's Hospital, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A Body Shape Index (ABSI) and normalized hip circumference (Hip Index, HI) have been recently shown to be strong risk factors for mortality and for cardiovascular disease in adults. We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic risk factors and obesity-related comorbidities in overweight and obese children and adolescents aged 2-18 years. We performed multivariate linear and logistic regression analyses with BMI, ABSI, and HI age and sex normalized z scores as predictors to examine the association with cardiometabolic risk markers (systolic and diastolic blood pressure, fasting glucose and insulin, total cholesterol and its components, transaminases, fat mass % detected by bioelectrical impedance analysis) and obesity-related conditions (including hepatic steatosis and metabolic syndrome). We recruited 217 patients (114 males), mean age 11.3 years. Multivariate linear regression showed a significant association of ABSI z score with 10 out of 15 risk markers expressed as continuous variables, while BMI z score showed a significant correlation with 9 and HI only with 1. In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. Overall, ABSI is an independent anthropometric index that was significantly associated with cardiometabolic risk markers in a pediatric population affected by overweight and obesity.

Indexed as

Body SizeAdolescentCardiovascular DiseasesChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleObesityOverweightRisk Factors

Identifiers

PMID29298340
PMCPMC5752028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.