Evidence map›Paper›PMID 29297959›Full record

ArticleOral diseases2018

P2Y

L T Woods, J M Camden, M G Khalafalla, M J Petris, L Erb, J L Ambrus, G A Weisman

Abstract read
In one paragraph

Article in Oral diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. P2YInternational journal of molecular sciences · 2025
    Review
  2. Therapeutic potential for P2YPurinergic signalling · 2023
    Review
  3. Article
  4. Purinergic Signaling in Oral Tissues.International journal of molecular sciences · 2022
    Review
  5. Early Dry Eye Disease Onset in a NOD.H-2h4 Mouse Model of Sjögren's Syndrome.Investigative ophthalmology & visual science · 2022
    Article
  6. The Involvement of Alarmins in the Pathogenesis of Sjögren's Syndrome.International journal of molecular sciences · 2022
    Review
  7. Review
  8. P2YArchives of oral biology · 2021
    Article
  9. Article
  10. P2YOral oncology · 2020
    Article
  11. Update of P2Y receptor pharmacology: IUPHAR Review 27.British journal of pharmacology · 2020
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

L T WoodsDepartment of Biochemistry, University of Missouri, Columbia, MO, USA.
J M CamdenDepartment of Biochemistry, University of Missouri, Columbia, MO, USA.
M G KhalafallaDepartment of Biochemistry, University of Missouri, Columbia, MO, USA.
M J PetrisDepartment of Biochemistry, University of Missouri, Columbia, MO, USA.
L ErbDepartment of Biochemistry, University of Missouri, Columbia, MO, USA.
J L AmbrusDepartment of Medicine, Division of Allergy, Immunology and Rheumatology, SUNY at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
G A WeismanDepartment of Biochemistry, University of Missouri, Columbia, MO, USA.ORCID http://orcid.org/0000-0002-3246-6353
University of Missouri · USNutrition Sciences (Belgium) · BEUniversity at Buffalo, State University of New York · US

Funding

VIP RECEPTORS AND SUBMANDIBULAR GLAND FUNCTIONR01DE007389 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 1988 to 2020
$7.6M
Restoring Salivary Gland Function by Reducing Nucleotide-induced InflammationR01DE023342 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 2014 to 2018
$2.9M
NIDCR NIH HHS R01 DE007389NIDCR NIH HHS R01 DE023342
6 · The paper itself

Abstract

objectiveInterleukin-14α-transgenic (IL-14αTG) mice develop an autoimmune exocrinopathy with characteristics similar to Sjögren's syndrome, including sialadenitis and hyposalivation. The P2Y MATERIALS AND

methodsIL-14αTG mice were bred with P2Y

resultsGenetic ablation of P2Y

conclusionsThe results of this study suggest that P2Y

Indexed as

B-LymphocytesT-LymphocytesAnimalsCalciumCells, CulturedDisease Models, AnimalEpithelial CellsFemaleGene ExpressionInterleukinsLymphocyte CountLymphotoxin-alphaMiceMice, KnockoutReceptors, Purinergic P2Y2SalivaCalciumInterleukinsLymphotoxin-alphaReceptors, Purinergic P2Y2TXLNA protein, mouseUridine TriphosphateVesicular Transport Proteinsautoimmunitylymphotoxin-alphanucleotidespurinergic receptorssalivary glandsSjögren's syndrome

Identifiers

PMID29297959
PMCPMC6644053
OpenAlexW2782180389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.