Evidence map›Paper›PMID 29297378›Full record

ArticleBMC systems biology2017

Identifying drug-pathway association pairs based on L

Jin-Xing Liu, Dong-Qin Wang, Chun-Hou Zheng, Ying-Lian Gao, Sha-Sha Wu, Jun-Liang Shang

Abstract read
In one paragraph

Article in BMC systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jin-Xing LiuSchool of Information Science and Engineering, Qufu Normal University, Rizhao, China.
Dong-Qin WangSchool of Information Science and Engineering, Qufu Normal University, Rizhao, China.
Chun-Hou ZhengSchool of Information Science and Engineering, Qufu Normal University, Rizhao, China. zhengch99@126.com.
Ying-Lian GaoLibrary of Qufu Normal University, Qufu Normal University, Rizhao, China. yinliangao@126.com.
Sha-Sha WuSchool of Information Science and Engineering, Qufu Normal University, Rizhao, China.
Jun-Liang ShangSchool of Information Science and Engineering, Qufu Normal University, Rizhao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional drug identification methods follow the "one drug-one target" thought. But those methods ignore the natural characters of human diseases. To overcome this limitation, many identification methods of drug-pathway association pairs have been developed, such as the integrative penalized matrix decomposition (iPaD) method. The iPaD method imposes the L

resultsTherefore, to improve the performance of the iPaD method, we propose a novel method named L

conclusionsBy applying the L

Indexed as

AlgorithmsComputational BiologyDatasets as TopicDrug DiscoveryHumansModels, TheoreticalDrug discoveryIntegrative penalized matrix decompositionL2,1-norm penaltySparse method

Identifiers

PMID29297378
PMCPMC5770056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.