Evidence map›Paper›PMID 29297372›Full record

ReviewCritical care (London, England)2017

Detailing the cardiovascular profile in shock patients.

Daniel De Backer

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07179276 (Veno-arterial Carbon Dioxide Partial Pressure Difference), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07179276 narecruitingnot on this mapstarted 2026, after this paper: background citation

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock: A Multicenter Prospective Randomized Trial (CARBON)

TypeinterventionalSponsorUniversity Hospital, Clermont-FerrandRan2026 to 2027Enrolled750ConditionsSepsis - to Reduce Mortality in the Intensive Care Unit, Septic ShockArmsCO2gap-guided resuscitation strategy
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Extracorporeal Cytokine Hemadsorption with oXirisJournal of clinical medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Observational
  9. Review
  10. The Use of Metaraminol as a Vasopressor in Critically Unwell Patients: A Narrative Review and a Survey of UK Practice.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2022
    Article
  11. Efficacy of Veno-Arterial Extracorporeal Life Support in Adult Patients with Refractory Cardiogenic Shock.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Improving the prognostic value of ∆PCOJournal of clinical monitoring and computing · 2020
    Article
  17. Minimizing catecholamines and optimizing perfusion.Critical care (London, England) · 2019
    Review
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Daniel De BackerDepartment of Intensive Care, CHIREC Hospitals, Université Libre de Bruxelles, Brussels, Belgium. ddebacke@ulb.ac.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluation of the cardiovascular profile of critically ill patients is one of the most important actions performed in critically ill patients. It allows recognition that the patient is in shock and characterization of the type of circulatory failure. This step is crucial to initiate supportive interventions and to cure the cause responsible for the development of shock. Evaluation of tissue perfusion allows identification of the patient insufficiently resuscitated and also to trigger therapeutic interventions. Monitoring tissue perfusion can be achieved by lactate, venoarterial gradients in PCO

Indexed as

Carbon DioxideCritical IllnessFluid TherapyHemodynamicsHumansLactic AcidMicrocirculationShockCarbon DioxideLactic Acid

Identifiers

PMID29297372
PMCPMC5751637

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.