Evidence map›Paper›PMID 29297245›Full record

ReviewNucleus (Austin, Tex.)2018

Super-resolution binding activated localization microscopy through reversible change of DNA conformation.

Aleksander Szczurek, Udo Birk, Hans Knecht, Jurek Dobrucki, Sabine Mai, Christoph Cremer

Abstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Non-coding RNAs in chromatin folding and nuclear organization.Cellular and molecular life sciences : CMLS · 2021
    Review
  3. Molecular Pathogenesis of Hodgkin Lymphoma: Past, Present, Future.International journal of molecular sciences · 2020
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aleksander Szczureka Institute of Molecular Biology , Mainz , Germany.ORCID 0000-0002-7363-5985
Udo Birka Institute of Molecular Biology , Mainz , Germany.ORCID 0000-0001-6313-7475
Hans Knechtd McGill, Jewish General Hospital , Montreal , Quebec , Canada.
Jurek Dobruckib Department of Cell Biophysics , Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University , Krakow , Poland.
Sabine Maie University of Manitoba, Cancer Care Manitoba , Winnipeg , Canada.
Christoph Cremera Institute of Molecular Biology , Mainz , Germany.ORCID 0000-0002-2090-6905

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methods of super-resolving light microscopy (SRM) have found an exponentially growing range of applications in cell biology, including nuclear structure analyses. Recent developments have proven that Single Molecule Localization Microscopy (SMLM), a type of SRM, is particularly useful for enhanced spatial analysis of the cell nucleus due to its highest resolving capability combined with very specific fluorescent labeling. In this commentary we offer a brief review of the latest methodological development in the field of SMLM of chromatin designated DNA Structure Fluctuation Assisted Binding Activated Localization Microscopy (abbreviated as fBALM) as well as its potential future applications in biology and medicine.

Indexed as

Nucleic Acid ConformationSingle Molecule ImagingBinding SitesCell NucleusDNADNAchromatinDNAfBALM, SMLMnucleussingle molecule localizationsuper-resolution microscopy

Identifiers

PMID29297245
PMCPMC5973136

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.