Trial reportInternational journal of behavioral medicine2018
One-Year Cardiovascular Prognosis of the Randomized, Controlled, Short-Term Heart Rate Variability Biofeedback Among Patients with Coronary Artery Disease.
Trial report in International journal of behavioral medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Bio-behavioral Interventions for Cardiovascular Diseases Rehabilitation: A Systematic Review on Heart Rate Variability Biofeedback and Nutrition.Applied psychophysiology and biofeedback · 2026Pooled it
- Effects of stress management interventions on heart rate variability in adults with cardiovascular disease: a systematic review and meta-analysis.Journal of behavioral medicine · 2024Pooled it
- Methods for Heart Rate Variability Biofeedback (HRVB): A Systematic Review and Guidelines.Applied psychophysiology and biofeedback · 2023Pooled it
- A meta-analysis investigating the outcomes and correlation between heart rate variability biofeedback training on depressive symptoms and heart rate variability outcomes versus standard treatment in comorbid adult populations.Acta bio-medica : Atenei Parmensis · 2023Pooled it
- Efficacy of bio- and neurofeedback for depression: a meta-analysis.Psychological medicine · 2022Pooled it
- Neurophysiological Approach by Self-Control of Your Stress-Related Autonomic Nervous System with Depression, Stress and Anxiety Patients.International journal of environmental research and public health · 2021Pooled it
- A meta-analysis on heart rate variability biofeedback and depressive symptoms.Scientific reports · 2021Pooled it
- Heart Rate Variability Biofeedback and Mental Stress Myocardial Flow Reserve: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Heart rate variability biofeedback in patients with functional dizziness.Journal of neurology · 2025Trial
- The Effects of Heart Rate Variability (HRV) Biofeedback on HRV Reactivity and Recovery During and After Anger Recall Task for Patients with Coronary Artery Disease.Applied psychophysiology and biofeedback · 2022Trial
- Autonomic Non-Responsiveness in HRV Biofeedback: A Narrative Conceptual Review and Future Directions for AI-Guided Closed-Loop Adaptive Systems.Medicina (Kaunas, Lithuania) · 2026Review
- Effects of Heart Rate Variability Biofeedback on Cardiac Autonomic Function in Patients with Cardiovascular Disease: A Systematic Review and Meta-analysis.Applied psychophysiology and biofeedback · 2026Review
- Heart Rate Variability Biofeedback Alleviates Subthreshold Depression by Reconstructing the Brain-Heart Axis via Habenular Network Functional Connectivity Modulation.CNS neuroscience & therapeutics · 2025Article
- The Bidirectional Relationship Between Myocardial Infarction and Depression: Risk Factors, Mechanisms, and Interventions.Biomedicines · 2025Review
- Implementation of Wearable Technology for Remote Heart Rate Variability Biofeedback in Cardiac Rehabilitation.Sensors (Basel, Switzerland) · 2025Article
- Article
- The Effect of Stress-Reducing Interventions on Heart Rate Variability in Cardiovascular Disease: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- The Utility of Heartrate and Heartrate Variability Biofeedback for the Improvement of Interoception across Behavioural, Physiological and Neural Outcome Measures: A Systematic Review.Brain sciences · 2024Review
- Assessment and Therapeutic Modulation of Heart Rate Variability: Potential Implications in Patients with COVID-19.Journal of cardiovascular development and disease · 2023Review
- Complexity and Entropy in Physiological Signals (CEPS): Resonance Breathing Rate Assessed Using Measures of Fractal Dimension, Heart Rate Asymmetry and Permutation Entropy.Entropy (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeHeart rate variability biofeedback (HRV-BF) is an effective psychophysiological intervention, with short-term effects of increased autonomic nervous system homeostasis, strengthened baroreflex sensitivity, and decreased hostility in patients with coronary artery disease (CAD). The study examined the 1-year HRV-BF effect on cardiovascular prognosis of these patients.
methodsOf 222 patients with CAD referred by cardiologists, 210 were screened and randomly assigned to the HRV-BF and control groups. All patients received psychophysiological assessment and completed psychological questionnaires at pre- and post-interventions and 1-year follow-up. The cardiovascular prognosis primary endpoints included hospital readmission, emergency revisits, and mortality.
resultsThe HRV-BF group had fewer all-cause readmissions (12.00 vs. 25.42%) and all-cause emergency visits (13.33 vs. 35.59%) than the control group. The low-frequency HRV in the HRV-BF group increased at post-intervention and 1-year follow-up compared with that at pre-intervention. Although no significant interaction effect was found in the standard deviation of the normal-to-normal intervals (F = 2.96, p = 0.055), it increased by 26.68% from pre- to post-intervention and 15.77% from pre-intervention to follow-up in the HRV-BF group. However, it decreased by 3.60% from pre- to post-intervention and increased by 1.99% from pre-intervention to follow-up in the control group. Depression and hostility scores decreased significantly at post-intervention and 1-year follow-up only in the HRV-BF group.
conclusionsThe long-term HRV-BF effect was confirmed by improved cardiovascular prognosis, increased cardiac autonomic homeostasis and baroreflex sensitivity, and decreased depression and hostility. HRV-BF is an effective psychophysiological intervention with short- and long-term effects in cardiac rehabilitation programs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.