Evidence map›Paper›PMID 29297106›Full record

ArticleMetabolic brain disease2018

Idalopirdine, a selective 5-HT

Magdalena Kotańska, Klaudia Lustyk, Adam Bucki, Monika Marcinkowska, Joanna Śniecikowska, Marcin Kołaczkowski

Open access · hybridAbstract read
In one paragraph

Article in Metabolic brain disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 40 citations in OpenAlex.

  1. Perspectives on obesity imaging: [International journal of obesity (2005) · 2025
    Article
  2. Article
  3. The Effect of KSK-94, a Dual Histamine HPharmaceuticals (Basel, Switzerland) · 2024
    Article
  4. WAY-208466, a 5-HTNeuroscience applied · 2024
    Article
  5. Impact of 5-HTCells · 2023
    Review
  6. Selective 5-HTPharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. KSK-74: Dual Histamine HInternational journal of molecular sciences · 2022
    Article
  8. Histamine HPharmaceuticals (Basel, Switzerland) · 2021
    Article
  9. The Phenoxyalkyltriazine Antagonists for 5-HTInternational journal of molecular sciences · 2021
    Article
  10. Article
  11. NovelPharmaceuticals (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Review
  14. Are the Hydantoin-1,3,5-triazine 5-HTMolecules (Basel, Switzerland) · 2019
    Article
  15. The 1,3,5-Triazine Derivatives as Innovative Chemical Family of 5-HTInternational journal of molecular sciences · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Magdalena KotańskaDepartment of Pharmacodynamics, Jagiellonian University, Medical College, 9 Medyczna Street, 30-688, Kraków, Poland. magda.dudek@uj.edu.pl.
Klaudia LustykDepartment of Pharmacodynamics, Jagiellonian University, Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Adam BuckiDepartment of Medicinal Chemistry, Jagiellonian University, Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Monika MarcinkowskaDepartment of Medicinal Chemistry, Jagiellonian University, Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Joanna ŚniecikowskaDepartment of Medicinal Chemistry, Jagiellonian University, Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Marcin KołaczkowskiDepartment of Medicinal Chemistry, Jagiellonian University, Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Jagiellonian University · PLAdamed (Poland) · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, from early childhood onwards, is a common societal problem. The overconsumption of sweet, salty and high-fat products are the main factors that cause excessive weight gain. It is therefore necessary to search for new drugs that affect satiety centers and reduce the sense of hunger and caloric intake. It has been suggested that the blockade of 5-HT

Indexed as

AnimalsBenzylaminesBody WeightDietEatingEnergy IntakeFluorocarbonsIndolesMaleObesityRats, WistarReceptors, SerotoninSerotonin AntagonistsWeight Gain(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amineBenzylaminesFluorocarbonsIndolesReceptors, Serotoninserotonin 6 receptorSerotonin Antagonists5-HT6 receptor antagonistAnorectic activityExcessive eating modelIdalopirdineLuAE58054

Identifiers

PMID29297106
PMCPMC5956042
OpenAlexW2781718743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.