Evidence map›Paper›PMID 29296973›Full record

ArticleBlood advances2017

High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis.

Katharine A Lombardo, David G Coffey, Alicia J Morales, Christopher S Carlson, Andrea M H Towlerton, Sarah E Gerdts, Francis K Nkrumah, Janet Neequaye, Robert J Biggar, Jackson Orem and 4 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Subtyping Burkitt Lymphoma by DNA Methylation.Genes, chromosomes & cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 6 countries.

Katharine A LombardoDivision of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA.ORCID 0000-0002-3344-5669
David G CoffeyDivision of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA.ORCID 0000-0003-3544-8836
Alicia J MoralesDivision of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA.
Christopher S CarlsonDivision of Public Health Sciences and.ORCID 0000-0003-0561-3538
Andrea M H TowlertonDivision of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA.
Sarah E GerdtsDivision of Vaccine and Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA.
Francis K NkrumahNoguchi Institute for Medical Research and.
Janet NeequayeDepartment of Child Health, Medical School, University of Ghana, Accra, Ghana.
Robert J BiggarInstitute of Health and Biotechnical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Jackson OremUganda Cancer Institute, Kampala, Uganda.ORCID 0000-0002-9824-346X
Corey CasperDivision of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA.ORCID 0000-0002-3609-661X
Sam M MbulaiteyeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Kishor G BhatiaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Edus H WarrenDivision of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA.ORCID 0000-0002-9570-2755
Fred Hutch Cancer Center · USUniversity of Washington · USNational Institutes of Health · USFaculty of Public Health · GBNoguchi Institute · JPQueensland University of Technology · AUUganda Cancer Institute · UGUniversity of Ghana · GH

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
Epidemiology and Natural History of Cancer-Associated VirusesZIACP010176 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MBULAITEYE, SAM M · 2009 to 2025
$33.7M
Chromosome Metabolism and Cancer Training GrantT32CA009657 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI EISENMAN, ROBERT NEIL · 1991 to 2020
$7.6M
NCI NIH HHS N01 CO012400NCI NIH HHS P30 CA015704NCI NIH HHS T32 CA009657
6 · The paper itself

Abstract

Burkitt lymphoma (BL), the most common pediatric cancer in sub-Saharan Africa, is a malignancy of antigen-experienced B lymphocytes. High-throughput sequencing (HTS) of the immunoglobulin heavy (

Identifiers

PMID29296973
PMCPMC5728594
OpenAlexW2600473255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.