Evidence map›Paper›PMID 29296913›Full record

ArticleBlood advances2017

Clinicopathologic consensus study of gray zone lymphoma with features intermediate between DLBCL and classical HL.

Monika Pilichowska, Stefania Pittaluga, Judith A Ferry, Jessica Hemminger, Hong Chang, Jennifer A Kanakry, Laurie H Sehn, Tatyana Feldman, Jeremy S Abramson, Athena Kritharis and 13 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 84 citations in OpenAlex.

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  9. Pediatric lymphomas: overview and diagnostic challenges.Virchows Archiv : an international journal of pathology · 2025
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  16. [Gray zone lymphoma: five cases report and literature review].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 16 institutions in 2 countries.

Monika PilichowskaDepartment of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA.
Stefania PittalugaLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Judith A FerryDepartment of Pathology, Massachusetts General Hospital, Boston, MA.
Jessica HemmingerDepartment of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH.
Hong ChangDivision of Hematology/Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Jennifer A KanakryDivision of Hematology/Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Laurie H SehnCentre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC, Canada.
Tatyana FeldmanHackensack University Medical Center, Hackensack, NJ.
Jeremy S AbramsonHematology/Oncology, Massachusetts General Hospital Cancer Center, Boston, MA.
Athena KritharisHematology/Oncology, Massachusetts General Hospital Cancer Center, Boston, MA.
Francisco J Hernandez-IlizaliturriRoswell Park Cancer Institute, Buffalo, NY.
Izidore S LossosDivision of Hematology/Oncology, University of Miami School of Medicine, Miami, FL.
Oliver W PressFred Hutchinson Cancer Research Center, Seattle, WA.
Timothy S FenskeDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI.
Jonathan W FriedbergDivision of Hematology/Oncology, University of Rochester, Rochester, NY.
Julie M VoseUniversity of Nebraska Medical Center, Omaha, NE.
Kristie A BlumDivision of Hematology, The Ohio State University, Columbus, OH.
Deepa JagadeeshCleveland Clinic, Cleveland, OH.
Bruce WodaDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA; and.
Gaurav K GuptaDepartment of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA.
Randy D GascoyneCentre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC, Canada.
Elaine S JaffeLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Andrew M EvensDivision of Hematology/Oncology, Tufts Medical Center, Boston, MA.ORCID 0000-0002-6900-1824
Tufts Medical Center · USMassachusetts General Hospital · USBC Cancer Agency · CANational Institutes of Health · USCleveland Clinic · USFred Hutch Cancer Center · USHackensack University Medical Center · USJohns Hopkins University · USMedical College of Wisconsin · USRoswell Park Comprehensive Cancer Center · USThe Ohio State University · USThe Ohio State University Wexner Medical Center · USUniversity of Massachusetts Chan Medical School · USUniversity of Miami · USUniversity of Nebraska Medical Center · USUniversity of Rochester · US

Funding

Hematopathology FellowshipZIEBC011241 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JAFFE, ELAINE · 2009 to 2025
$11.1M
6 · The paper itself

Abstract

Gray zone lymphoma (GZL) is described as sharing features with classical Hodgkin lymphoma (cHL) and diffuse large B-cell lymphoma (DLBCL). However, there remains complexity in establishing diagnosis, delineating prognosis, and determining optimum therapy. Sixty-eight cases diagnosed as GZL across 15 North American academic centers were evaluated by central pathology review to achieve consensus. Of these, only 26 (38%) were confirmed as GZL. Morphology was critical to GZL consensus diagnosis (eg, tumor cell richness); immunohistochemistry showed universal B-cell derivation, frequent CD30 expression, and rare Epstein-Barr virus (EBV) positivity (CD20

Identifiers

PMID29296913
PMCPMC5728632
OpenAlexW2774408258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.