Evidence map›Paper›PMID 29296855›Full record

ArticleBlood advances2017

Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT.

Angela R Smith, Ioanna A Rota, Stefano Maio, Michel J Massaad, Troy C Lund, Luigi D Notarangelo, Georg A Holländer, Bruce R Blazar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism.Acta crystallographica. Section F, Structural biology communications · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Angela R SmithDivision of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.
Ioanna A RotaDepartment of Paediatrics and the Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Stefano MaioDepartment of Paediatrics and the Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Michel J MassaadDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA; and.
Troy C LundDivision of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.
Luigi D NotarangeloImmune Deficiency Genetics Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Georg A HolländerDepartment of Paediatrics and the Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Bruce R BlazarDivision of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.
University of Minnesota · USMRC Weatherall Institute of Molecular Medicine · GBBoston Children's Hospital · USNational Institutes of Health · USUniversity of Oxford · GB

Funding

Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Mark J Osborn · 1995 to 2026
$48.2M
Characterization of the cellular and molecular bases of inborn errors of immunityZIAAI001222 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NOTARANGELO, LUIGI · 2017 to 2025
$15.2M
NCI NIH HHS P01 CA065493
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29296855
PMCPMC5728290
OpenAlexW2765209143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.