Evidence map›Paper›PMID 29296832›Full record

ArticleBlood advances2017

A unique microenvironment in the developing liver supports the expansion of megakaryocyte progenitors.

Nathalie Brouard, Camille Jost, Nadine Matthias, Camille Albrecht, Sébastien Egard, Poojabahen Gandhi, Catherine Strassel, Tomoko Inoue, Daisuke Sugiyama, Paul J Simmons and 2 more

Abstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. International journal of molecular sciences · 2023
    Article
  2. Article
  3. Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen.International journal of molecular sciences · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nathalie BrouardUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.ORCID 0000-0003-0727-9377
Camille JostUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.
Nadine MatthiasCenter for Stem Cell Research, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX.
Camille AlbrechtUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.
Sébastien EgardUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.
Poojabahen GandhiCenter for Stem Cell Research, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX.
Catherine StrasselUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.
Tomoko InoueCenter for Clinical and Translational Research, Kyushu University Hospital, Fukuoka, Japan; and.
Daisuke SugiyamaCenter for Clinical and Translational Research, Kyushu University Hospital, Fukuoka, Japan; and.
Paul J SimmonsCenter for Stem Cell Research, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX.
Christian GachetUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.ORCID 0000-0003-1303-4210
Francois LanzaUniversité de Strasbourg, INSERM, Etablissement Français du Sang-Alsace, Biologie et Pharmacologie des Plaquettes Sanguines Unité Mixte de Recherche-S 949, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fetal liver is the site of a major expansion of the hematopoietic stem cell (HSC) pool and is also a privileged organ to study megakaryocyte progenitor differentiation. We identified in the mouse fetal liver at day 13.5 a discrete stromal cell population harboring a CD45

Identifiers

PMID29296832
PMCPMC5728093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.