Evidence map›Paper›PMID 29296828›Full record

ArticleBlood advances2017

Gene editing rescue of a novel

Cédric Cleyrat, Romain Girard, Eun H Choi, Éric Jeziorski, Thierry Lavabre-Bertrand, Sylvie Hermouet, Serge Carillo, Bridget S Wilson

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
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  8. Review
  9. Inherited Platelet Disorders: An Updated Overview.International journal of molecular sciences · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Cédric CleyratDepartment of Pathology and Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, NM.
Romain GirardDepartment of Pathology and Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, NM.
Eun H ChoiDepartment of Pathology and Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, NM.
Éric JeziorskiService de Pédiatrie III, Hôpital Arnaud de Villeneuve, Montpellier, France.
Thierry Lavabre-BertrandUniversity Hospital of Nîmes, Laboratory of Clinical Cytology and Cytogenetics, Nîmes, France; and.
Sylvie HermouetCentre de Recherche en Cancérologie et Immunologie Nantes-Angers, INSERM U1232, Institut de Recherche en Santé 2-Biotech, Nantes, France.
Serge CarilloUniversity Hospital of Nîmes, Laboratory of Clinical Cytology and Cytogenetics, Nîmes, France; and.
Bridget S WilsonDepartment of Pathology and Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, NM.
University of New Mexico · USUniversité de Nîmes · FRHôpital Arnaud de Villeneuve · FRInserm · FRNew Mexico Cancer Center · US

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LIDKE, KEITH A · 2009 to 2018
$26.1M
Development of Small Molecule Radiation SensitizersR01CA140409 · NCI · VANDERBILT UNIVERSITY · PI FREEMAN, MICHAEL L., KONJETI, SEKHAR RAJA · 2010 to 2014
$1.7M
NCI NIH HHS P30 CA118100NCI NIH HHS R01 CA140409NIGMS NIH HHS P50 GM085273
6 · The paper itself

Abstract

Thrombopoietin (Tpo) and its receptor (Mpl) are the principal regulators of early and late thrombopoiesis and hematopoietic stem cell maintenance. Mutations in

Identifiers

PMID29296828
PMCPMC5728092
OpenAlexW2757641528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.