ArticleBlood advances2017
Disease severity and slower psychomotor speed in adults with sickle cell disease.
Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Accelerated brain atrophy in sickle cell anemia despite chronic exchange transfusion therapy-A case report.Radiology case reports · 2026Article
- Determinants of cognitive dysfunction in adults with sickle cell-related stroke or suspected neurological morbidity.Blood advances · 2024Article
- Neuroinflammation underlies the development of social stress induced cognitive deficit in sickle cell disease.bioRxiv : the preprint server for biology · 2024Article
- Comprehensive assessment of cognitive function in adults with moderate and severe sickle cell disease.American journal of hematology · 2022Article
- Neurocognitive functioning in preschool children with sickle cell disease.Pediatric blood & cancer · 2022Article
- Analysis of hippocampal subfields in sickle cell disease using ultrahigh field MRI.NeuroImage. Clinical · 2021Article
- Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Protocol for an Efficacy and Implementation Study.JMIR research protocols · 2020Article
- Development of the InCharge Health Mobile App to Improve Adherence to Hydroxyurea in Patients With Sickle Cell Disease: User-Centered Design Approach.JMIR mHealth and uHealth · 2020Article
- Association of sickle cell trait with measures of cognitive function and dementia in African Americans.eNeurologicalSci · 2019Article
- Measuring success: utility of biomarkers in sickle cell disease clinical trials and care.Hematology. American Society of Hematology. Education Program · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Psychomotor slowing is common in children with sickle cell disease (SCD), but little is known about its severity in adults. We conducted a cross-sectional study to quantify psychomotor speed, measured with the digit symbol substitution test (DSST), in relationship with disease severity in adults with SCD attending an outpatient clinic (n = 88, age 36.3 years). Genotype was used to group patients in "severe" (homozygous for hemoglobin S or compound heterozygous with β
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.