Evidence map›Paper›PMID 29296819›Full record

ArticleBlood advances2017

Impact of genomic alterations on outcomes in myelofibrosis patients undergoing JAK1/2 inhibitor therapy.

Jay Y Spiegel, Caroline McNamara, James A Kennedy, Tony Panzarella, Andrea Arruda, Tracy Stockley, Mahadeo Sukhai, Mariam Thomas, Justyna Bartoszko, Jenny Ho and 11 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03959371 (Observational, Retrospective and Prospective Study on the Use of Ruxolitinib in Myelofibrosis Patients in Lombardy, Italy), which is not on this map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03959371 unknown statusnot on this map

Observational, Retrospective and Prospective Study on the Use of Ruxolitinib in Myelofibrosis Patients in Lombardy, Italy

TypeobservationalSponsorMargherita MaffioliRan2017 to 2021Enrolled620ConditionsMyelofibrosisArmsRuxolitinib
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Ruxolitinib Therapy Followed by Reduced-Intensity Conditioning for Hematopoietic Cell Transplantation for Myelofibrosis: Myeloproliferative Disorders Research Consortium 114 Study.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
    Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Advances in Stem Cell Transplantation for Myelofibrosis.Current hematologic malignancy reports · 2024
    Review
  10. Article
  11. Prognostic and Predictive Models in Myelofibrosis.Current hematologic malignancy reports · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Jay Y SpiegelDepartment of Medicine, University of Toronto, Toronto, Canada; and.
Caroline McNamaraDepartment of Medical Oncology and Hematology.
James A KennedyDepartment of Medical Oncology and Hematology.
Tony PanzarellaDepartment of Biostatistics, and.
Andrea ArrudaDepartment of Medical Oncology and Hematology.
Tracy StockleyAdvanced Molecular Diagnostics Laboratory, University Health Network, Princess Margaret Cancer Centre, Toronto, Canada.
Mahadeo SukhaiAdvanced Molecular Diagnostics Laboratory, University Health Network, Princess Margaret Cancer Centre, Toronto, Canada.
Mariam ThomasAdvanced Molecular Diagnostics Laboratory, University Health Network, Princess Margaret Cancer Centre, Toronto, Canada.
Justyna BartoszkoDepartment of Medicine, University of Toronto, Toronto, Canada; and.
Jenny HoDepartment of Medical Oncology and Hematology.
Nancy SiddiqDepartment of Medical Oncology and Hematology.
Dawn MazeDepartment of Medical Oncology and Hematology.
Aaron SchimmerDepartment of Medical Oncology and Hematology.
Andre SchuhDepartment of Medical Oncology and Hematology.
Hassan SibaiDepartment of Medical Oncology and Hematology.
Karen YeeDepartment of Medical Oncology and Hematology.
Jamie ClaudioDepartment of Medical Oncology and Hematology.
Rebecca DevlinDepartment of Medical Oncology and Hematology.
Mark D MindenDepartment of Medical Oncology and Hematology.
Suzanne Kamel-ReidAdvanced Molecular Diagnostics Laboratory, University Health Network, Princess Margaret Cancer Centre, Toronto, Canada.
Vikas GuptaDepartment of Medical Oncology and Hematology.
Princess Margaret Cancer Centre · CAUniversity Health Network · CAUniversity of Toronto · CACancer Research And Biostatistics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In myelofibrosis (MF), driver mutations in

Identifiers

PMID29296819
PMCPMC5728340
OpenAlexW2760217744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.