Evidence map›Paper›PMID 29296732›Full record

ArticleBlood advances2017

Chromatin dynamics during the differentiation of long-term hematopoietic stem cells to multipotent progenitors.

Xiang Yu, Chao Wu, Dheeraj Bhavanasi, Hong Wang, Brian D Gregory, Jian Huang

Abstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiang YuDepartment of Biology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-5730-8802
Chao WuDepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA.
Dheeraj BhavanasiDivision of Hematology-Oncology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA; and.
Hong WangCenter for Metabolic Disease Research, Department of Pharmacology, Temple University Lewis Katz School of Medicine, Philadelphia, PA.
Brian D GregoryDepartment of Biology, University of Pennsylvania, Philadelphia, PA.
Jian HuangDepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA.ORCID 0000-0002-1649-0038

Funding

Signaling pathways regulated by GSK3 in hematopoietic stem cellR00HL107747 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI HUANG, JIAN · 2013 to 2015
$726k
NHLBI NIH HHS R00 HL107747
6 · The paper itself

Abstract

ATAC-seq provides genome-wide chromatin state in 3 cell types of hematopoietic stem/progenitor cells.Transcription factor cohorts are associated with dynamic changes of open chromatin during the differentiation of LT/ST-HSCs to MPPs.

Identifiers

PMID29296732
PMCPMC5737588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.