Evidence map›Paper›PMID 29296716›Full record

ArticleBlood advances2017

MRD detection in multiple myeloma: comparison between MSKCC 10-color single-tube and EuroFlow 8-color 2-tube methods.

Mikhail Roshal, Juan A Flores-Montero, Qi Gao, Maesa Koeber, Jessica Wardrope, Brian G M Durie, Ahmet Dogan, Alberto Orfao, Ola Landgren

Abstract read
In one paragraph

Article in Blood advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

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  4. Pilot Study of Bortezomib and Dexamethasone Pre- and Post-Risk-Adapted Autologous Stem Cell Transplantation in AL Amyloidosis.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
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  10. Robust CD4medRxiv : the preprint server for health sciences · 2025
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  15. Article
  16. Article
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mikhail RoshalHematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Juan A Flores-MonteroCancer Research Institute of Salamanca, Universidad de Salamanca-Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain.
Qi GaoHematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Maesa KoeberMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; and.
Jessica WardropeHematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Brian G M DurieInternational Myeloma Foundation, North Hollywood, CA.
Ahmet DoganHematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Alberto OrfaoCancer Research Institute of Salamanca, Universidad de Salamanca-Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain.
Ola LandgrenMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; and.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

In patients with multiple myeloma, obtaining posttreatment minimal residual disease (MRD) negativity is associated with longer progression-free survival and overall survival. Here, we compared the diagnostic performance of a single 10-color tube with that of a EuroFlow 8-color 2-tube panel for MRD testing. Bone marrow samples from 41 multiple myeloma patients were tested in parallel using the 2 approaches. Compared with the sum of the cells from the EuroFlow two 8-color tubes, the Memorial Sloan Kettering Cancer Center (MSKCC) single 10-color tube had a slight reduction in total cell number with a mean ratio of 0.85 (range, 0.57-1.46;

Identifiers

PMID29296716
PMCPMC5728052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.